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Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load

Academic Article
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Overview

authors

  • McLaren, P. J.
  • Coulonges, C.
  • Bartha, I.
  • Lenz, T. L.
  • Deutsch, A. J.
  • Bashirova, A.
  • Buchbinder, S.
  • Carrington, M. N.
  • Cossarizza, A.
  • Dalmau, J.
  • De Luca, A.
  • Goedert, J. J.
  • Gurdasani, D.
  • Haas, D. W.
  • Herbeck, J. T.
  • Johnson, E. O.
  • Kirk, G. D.
  • Lambotte, O.
  • Luo, M.
  • Mallal, S.
  • van Manen, D.
  • Martinez-Picado, J.
  • Meyer, L.
  • Miro, J.
  • Mullins, J. I.
  • Obel, N.
  • Poli, G.
  • Sandhu, M. S.
  • Schuitemaker, H.
  • Shea, P. R.
  • Theodorou, I.
  • Walker, B. D.
  • Weintrob, A. C.
  • Winkler, C. A.
  • Wolinsky, S. M.
  • Raychaudhuri, S.
  • Goldstein, D. B.
  • Telenti, Amalio
  • de Bakker, P. I. W.
  • Zagury, J. F.
  • Fellay, J.

publication date

  • November 2015

journal

  • Proceedings of the National Academy of Sciences of the United States of America  Journal

subject areas

  • Adult
  • Alleles
  • Amino Acids
  • Chromosomes, Human, Pair 3
  • Genetic Predisposition to Disease
  • Genome-Wide Association Study
  • HIV-1
  • HLA-B Antigens
  • Host-Pathogen Interactions
  • Humans
  • Inheritance Patterns
  • Physical Chromosome Mapping
  • Polymorphism, Single Nucleotide
  • Receptors, CCR5
  • Viral Load
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Research

keywords

  • GWAS
  • HIV-1 control
  • genomics
  • heritability
  • infectious disease
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Identity

PubMed Central ID

  • PMC4664299

International Standard Serial Number (ISSN)

  • 0027-8424

Digital Object Identifier (DOI)

  • 10.1073/pnas.1514867112

PubMed ID

  • 26553974
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Additional Document Info

start page

  • 14658

end page

  • 14663

volume

  • 112

issue

  • 47

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