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Mutations of complement factor I and potential mechanisms of neuroinflammation in acute hemorrhagic leukoencephalitis

Academic Article
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Overview

authors

  • Broderick, L.
  • Gandhi, C.
  • Mueller, J. L.
  • Putnam, Christopher
  • Shayan, K.
  • Giclas, P. C.
  • Peterson, K. S.
  • Aceves, S. S.
  • Sheets, R. M.
  • Peterson, B. M.
  • Newbury, R. O.
  • Hoffman, H. M.
  • Bastian, J. F.

publication date

  • January 2013

journal

  • Journal of Clinical Immunology  Journal

subject areas

  • Adolescent
  • Adult
  • Child
  • Complement Activation
  • Complement C3
  • Complement Factor I
  • Complement Membrane Attack Complex
  • Female
  • HEK293 Cells
  • Humans
  • Immunophenotyping
  • Inflammation
  • Interleukin-1
  • Leukoencephalitis, Acute Hemorrhagic
  • Male
  • Mutation, Missense
  • Neurons
  • Pedigree
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Research

keywords

  • Acute hemorrhagic leukoencephalitis
  • IL-1
  • IL-1 receptor antagonist
  • complement factor I
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Identity

PubMed Central ID

  • PMC3540165

International Standard Serial Number (ISSN)

  • 0271-9142

Digital Object Identifier (DOI)

  • 10.1007/s10875-012-9767-z

PubMed ID

  • 22926405
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Additional Document Info

start page

  • 162

end page

  • 171

volume

  • 33

issue

  • 1

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