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The cataract-inducing S50P mutation in Cx50 dominantly alters the channel gating of wild-type lens connexins

Academic Article
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Overview

authors

  • DeRosa, A. M.
  • Xia, C. H.
  • Gong, Xiaohua
  • White, T. W.

publication date

  • December 2007

journal

  • Journal of Cell Science  Journal

subject areas

  • Animals
  • Cataract
  • Connexins
  • Electrophysiology
  • Eye Proteins
  • Female
  • Gap Junctions
  • Genetic Engineering
  • HeLa Cells
  • Heterozygote
  • Humans
  • Immunohistochemistry
  • Ion Channel Gating
  • Lens, Crystalline
  • Mice
  • Mice, Knockout
  • Microinjections
  • Models, Biological
  • Mutation
  • Oocytes
  • Patch-Clamp Techniques
  • Transfection
  • Xenopus
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Research

keywords

  • cataract
  • connexin
  • gating
  • lens
  • mutation
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Identity

International Standard Serial Number (ISSN)

  • 0021-9533

Digital Object Identifier (DOI)

  • 10.1242/jcs.012237

PubMed ID

  • 18003700
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Additional Document Info

start page

  • 4107

end page

  • 4116

volume

  • 120

issue

  • 23

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