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Blockade of 2-arachidonoylglycerol hydrolysis produces antidepressant-like effects and enhances adult hippocampal neurogenesis and synaptic plasticity

Academic Article
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Overview

related to degree

  • Long, Jonathan, Ph.D. in Chemistry, Scripps Research 2007 - 2011

authors

  • Zhang, Z.
  • Wang, W.
  • Zhong, P.
  • Liu, S. J.
  • Long, Jonathan
  • Zhao, L.
  • Gao, H. Q.
  • Cravatt, Benjamin
  • Liu, Q. S.

publication date

  • January 2015

journal

  • Hippocampus  Journal

subject areas

  • Animals
  • Anti-Anxiety Agents
  • Antidepressive Agents
  • Arachidonic Acids
  • Behavior, Animal
  • Benzodioxoles
  • Cannabinoid Receptor Agonists
  • Dentate Gyrus
  • Depression
  • Endocannabinoids
  • Glycerides
  • Hydrolysis
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Monoacylglycerol Lipases
  • Neurogenesis
  • Neuronal Plasticity
  • Piperidines
  • Stress, Psychological
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Research

keywords

  • CB1 receptor
  • chronic unpredictable stress
  • depression
  • endocannabinoid
  • neurogenesis
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Identity

PubMed Central ID

  • PMC4517601

International Standard Serial Number (ISSN)

  • 1050-9631

Digital Object Identifier (DOI)

  • 10.1002/hipo.22344

PubMed ID

  • 25131612
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Additional Document Info

start page

  • 16

end page

  • 26

volume

  • 25

issue

  • 1

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