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Unlocking the bottleneck in forward genetics using whole-genome sequencing and identity by descent to isolate causative mutations

Academic Article
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Overview

related to degree

  • Siggs, Owen Marc, D.Phil. in Biology, University of Oxford , Joint graduate program with The Scripps Research Institute 2007 - 2012

authors

  • Bull, K. R.
  • Rimmer, A. J.
  • Siggs, Owen Marc
  • Miosge, L. A.
  • Roots, C. M.
  • Enders, A.
  • Bertram, E. M.
  • Crockford, T. L.
  • Whittle, B.
  • Potter, P. K.
  • Simon, M. M.
  • Mallon, A. M.
  • Brown, S. D. M.
  • Beutler, B.
  • Goodnow, C. C.
  • Lunter, G.
  • Cornall, R. J.

publication date

  • 2013

journal

  • PLoS Genetics  Journal

subject areas

  • Animals
  • Chromosome Mapping
  • Disease Models, Animal
  • Ethylnitrosourea
  • Genes, Dominant
  • Genes, Recessive
  • Genome
  • Humans
  • Mice
  • Mutagenesis
  • Mutation
  • Phenotype
  • Sequence Analysis, DNA
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Identity

PubMed Central ID

  • PMC3561070

International Standard Serial Number (ISSN)

  • 1553-7404

Digital Object Identifier (DOI)

  • 10.1371/journal.pgen.1003219

PubMed ID

  • 23382690
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Additional Document Info

volume

  • 9

issue

  • 1

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