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High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations

Academic Article
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Overview

authors

  • Mott, B. T.
  • Eastman, R. T.
  • Guha, R.
  • Sherlach, K. S.
  • Siriwardana, A.
  • Shinn, P.
  • McKnight, C.
  • Michael, S.
  • Lacerda-Queiroz, N.
  • Patel, Paresma
  • Khine, P.
  • Sun, H.
  • Kasbekar, M.
  • Aghdam, N.
  • Fontaine, S. D.
  • Liu, D.
  • Mierzwa, T.
  • Mathews-Griner, L. A.
  • Ferrer, M.
  • Renslo, A. R.
  • Inglese, J.
  • Yuan, J.
  • Roepe, P. D.
  • Su, X. Z.
  • Thomas, C. J.

publication date

  • 2015

journal

  • Scientific Reports  Journal

subject areas

  • Animals
  • Antimalarials
  • Autophagy
  • Calcium
  • Cluster Analysis
  • Disease Models, Animal
  • Drug Antagonism
  • Drug Synergism
  • Drug Therapy, Combination
  • High-Throughput Screening Assays
  • Homeostasis
  • Humans
  • Inhibitory Concentration 50
  • Malaria
  • Mice
  • Mitochondria
  • Oxidative Stress
  • Parasitic Sensitivity Tests
  • Phagosomes
  • Phosphatidylinositol 3-Kinases
  • Plasmodium
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Identity

PubMed Central ID

  • PMC4585899

International Standard Serial Number (ISSN)

  • 2045-2322

Digital Object Identifier (DOI)

  • 10.1038/srep13891

PubMed ID

  • 26403635
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Additional Document Info

volume

  • 5

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