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Combined inhibition of FAAH and COX produces enhanced anti-allodynic effects in mouse neuropathic and inflammatory pain models

Academic Article
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Overview

authors

  • Grim, T. W.
  • Ghosh, S.
  • Hsu, K. L.
  • Cravatt, Benjamin
  • Kinsey, S. G.
  • Lichtman, A. H.

publication date

  • September 2014

journal

  • Pharmacology, Biochemistry and Behavior  Journal

subject areas

  • Amidohydrolases
  • Animals
  • Disease Models, Animal
  • Enzyme Inhibitors
  • Hyperalgesia
  • Inflammation
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Neuralgia
  • Prostaglandin-Endoperoxide Synthases
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Research

keywords

  • Cyclooxygenase (COX)
  • Endogenous cannabinoid (endocannabinoid)
  • Fatty add amide hydrolase
  • Inflammatory pain
  • Neuropathic pain
  • Prostaglandins
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Identity

PubMed Central ID

  • PMC4206939

International Standard Serial Number (ISSN)

  • 0091-3057

Digital Object Identifier (DOI)

  • 10.1016/j.pbb.2014.07.008

PubMed ID

  • 25058512
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Additional Document Info

start page

  • 405

end page

  • 411

volume

  • 124

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