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An evolutionary model encompassing substrate specificity and reactivity of type I polyketide synthase thioesterases

Academic Article
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Overview

authors

  • Hari, T. P. A.
  • Labana, P.
  • Boileau, M.
  • Boddy, Christopher Noyce

publication date

  • December 2014

journal

  • ChemBioChem  Journal

subject areas

  • Bacteria
  • Evolution, Molecular
  • Macrolides
  • Phylogeny
  • Polyketide Synthases
  • Substrate Specificity
  • Thiolester Hydrolases
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Research

keywords

  • macrodiolide
  • macrolactone
  • screening hypothesis
  • substrate selectivity
  • thioesterase
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Identity

International Standard Serial Number (ISSN)

  • 1439-4227

Digital Object Identifier (DOI)

  • 10.1002/cbic.201402475

PubMed ID

  • 25354333
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Additional Document Info

start page

  • 2656

end page

  • 2661

volume

  • 15

issue

  • 18

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