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Leveraging the Knorr pyrazole synthesis for the facile generation of thioester surrogates for use in native chemical ligation

Academic Article
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Overview

related to degree

  • Flood, Dillon, Ph.D. in Chemical Biology, Scripps Research 2016 -
  • Bird, Michael, Ph.D. in Chemical Biology, Scripps Research 2016 -
  • Cistrone, Philip A., Ph.D. in Chemical Biology, Scripps Research 2013 - 2019

authors

  • Flood, Dillon
  • Hintzen, J. C. J.
  • Bird, Michael
  • Cistrone, Philip A.
  • Chen, Jason Shih-Hao
  • Dawson, Philip

publication date

  • September 2018

journal

  • Angewandte Chemie-International Edition  Journal
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Research

keywords

  • chemoselective ligation
  • native chemical ligation
  • peptide hydrazides
  • protein synthesis
  • pyrazoles
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Identity

PubMed Central ID

  • PMC6126375

International Standard Serial Number (ISSN)

  • 1433-7851

Digital Object Identifier (DOI)

  • 10.1002/anie.201805191

PubMed ID

  • 29908104
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Additional Document Info

start page

  • 11634

end page

  • 11639

volume

  • 57

issue

  • 36

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