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Nucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies

Academic Article
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Overview

authors

  • Bowers, P. M.
  • Verdino, P.
  • Wang, Z.
  • da Silva Correia, J.
  • Chhoa, M.
  • Macondray, G.
  • Do, M.
  • Neben, T. Y.
  • Horlick, R. A.
  • Stanfield, Robyn
  • Wilson, Ian
  • King, D. J.

publication date

  • November 2014

journal

  • Journal of Biological Chemistry  Journal

subject areas

  • Complementarity Determining Regions
  • Cytidine Deaminase
  • Female
  • Humans
  • INDEL Mutation
  • Male
  • Somatic Hypermutation, Immunoglobulin
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Identity

PubMed Central ID

  • PMC4246108

International Standard Serial Number (ISSN)

  • 0021-9258

Digital Object Identifier (DOI)

  • 10.1074/jbc.M114.607176

PubMed ID

  • 25320089
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Additional Document Info

start page

  • 33557

end page

  • 33567

volume

  • 289

issue

  • 48

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