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Analysis of HIF-1 inhibition by manassantin A and analogues with modified tetrahydrofuran configurations

Academic Article
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Overview

authors

  • Kasper, A. C.
  • Moon, E. J.
  • Hu, X.
  • Park, Y.
  • Wooten, C. M.
  • Kim, H.
  • Yang, W.
  • Dewhirst, M. W.
  • Hong, Jiyong

publication date

  • July 2009

journal

  • Bioorganic & Medicinal Chemistry Letters  Journal

subject areas

  • Animals
  • Cell Line
  • Furans
  • Hypoxia-Inducible Factor 1
  • Lignans
  • Mice
  • Vascular Endothelial Growth Factor A
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Research

keywords

  • 2,3-cis-3,4-trans-4,5-cis-Tetrahydrofuran
  • 2,3-cis-3,4-trans-4,5-trans-Tetrahydrofuran
  • 2,3-trans-3,4-trans-4,5-trans-Tetrahydrofuran
  • Conformation-activity relationship
  • Hypoxia
  • Hypoxia inducible factor-1
  • Manassantin A
  • Tetrahydrofuran analogue
  • Tetrahydrofuran configuration
  • Vascular endothelial growth factor
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Identity

PubMed Central ID

  • PMC2709708

International Standard Serial Number (ISSN)

  • 0960-894X

Digital Object Identifier (DOI)

  • 10.1016/j.bmcl.2009.04.071

PubMed ID

  • 19423348
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Additional Document Info

start page

  • 3783

end page

  • 3786

volume

  • 19

issue

  • 14

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