Scripps VIVO scripps research logo

  • Index
  • Log in
  • Home
  • People
  • Organizations
  • Research
  • Events
Search form

Synthesis and evaluation of analogs of 5 '-(((Z)-4-amino-2-butenyl)methylamino)-5 '-deoxyadenosine (MDL 73811, or AbeAdo) - An inhibitor of S-adenosylmethionine decarboxylase with antitrypanosomal activity

Academic Article
uri icon
  • Overview
  • Research
  • Identity
  • Additional Document Info
  • View All
scroll to property group menus

Overview

authors

  • Brockway, A. J.
  • Volkov, O. A.
  • Cosner, C. C.
  • Macmillan, Karen Smith
  • Wring, S. A.
  • Richardson, T. E.
  • Peel, M.
  • Phillips, M. A.
  • De Brabander, J. K.

publication date

  • October 2017

journal

  • Bioorganic & Medicinal Chemistry  Journal

subject areas

  • Adenosylmethionine Decarboxylase
  • Animals
  • Deoxyadenosines
  • Disease Models, Animal
  • Dose-Response Relationship, Drug
  • Enzyme Inhibitors
  • Mice
  • Molecular Conformation
  • Parasitic Sensitivity Tests
  • Structure-Activity Relationship
  • Trypanocidal Agents
  • Trypanosoma brucei brucei
  • Trypanosomiasis, African
scroll to property group menus

Research

keywords

  • Antitrypanosomal
  • Human African Trypanosomiasis
  • Metabolism
  • Permeability
  • S-adenosylmethionine decarboxylase
  • Structure-activity relationship
scroll to property group menus

Identity

PubMed Central ID

  • PMC5632197

International Standard Serial Number (ISSN)

  • 0968-0896

Digital Object Identifier (DOI)

  • 10.1016/j.bmc.2017.07.063

PubMed ID

  • 28807574
scroll to property group menus

Additional Document Info

start page

  • 5433

end page

  • 5440

volume

  • 25

issue

  • 20

©2021 The Scripps Research Institute | Terms of Use | Powered by VIVO

  • About
  • Contact Us
  • Support