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Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth

Academic Article
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  • Overview
  • Identity
  • Additional Document Info
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Overview

authors

  • Sangodkar, J.
  • Perl, A.
  • Tohme, R.
  • Kiselar, J.
  • Kastrinsky, David
  • Zaware, N.
  • Izadmehr, S.
  • Mazhar, S.
  • Wiredja, D. D.
  • O'Connor, C. M.
  • Hoon, D.
  • Dhawan, N. S.
  • Schlatzer, D.
  • Yao, S.
  • Leonard, D.
  • Borczuk, A. C.
  • Gokulrangan, G.
  • Wang, L.
  • Svenson, E.
  • Farrington, C. C.
  • Yuan, E.
  • Avelar, R. A.
  • Stachnik, A.
  • Smith, B.
  • Gidwani, V.
  • Giannini, H. M.
  • McQuaid, D.
  • McClinch, K.
  • Wang, Z.
  • Levine, A. C.
  • Sears, R. C.
  • Chen, E. Y.
  • Duan, Q. N.
  • Datt, M.
  • Haider, S.
  • Ma'ayan, A.
  • DiFeo, A.
  • Sharma, N.
  • Galsky, M. D.
  • Brautigan, D. L.
  • Ioannou, Y. A.
  • Xu, W.
  • Chance, M. R.
  • Ohlmeyer, M.
  • Narla, G.

publication date

  • 2017

journal

  • Journal of Clinical Investigation  Journal

subject areas

  • Animals
  • Antineoplastic Agents
  • Cell Line, Tumor
  • Cell Survival
  • Drug Resistance, Neoplasm
  • Enzyme Activation
  • Enzyme Activators
  • Humans
  • Male
  • Mice, Inbred BALB C
  • Mice, Nude
  • Mice, Transgenic
  • Protein Binding
  • Protein Phosphatase 2
  • Proto-Oncogene Proteins p21(ras)
  • Signal Transduction
  • Tumor Burden
  • Xenograft Model Antitumor Assays
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Identity

PubMed Central ID

  • PMC5451217

International Standard Serial Number (ISSN)

  • 0021-9738

Digital Object Identifier (DOI)

  • 10.1172/jci89548

PubMed ID

  • 28504649
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Additional Document Info

start page

  • 2081

end page

  • 2090

volume

  • 127

issue

  • 6

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