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Synthesis and structure-activity relationship of (1-halo-2-naphthyl) carbamate-based inhibitors of KIAA1363 (NCEH1/AADACL1)

Academic Article
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Overview

authors

  • Shreder, K. R.
  • Lin, E. C. K.
  • Wu, J.
  • Cajica, J.
  • Amantea, C. M.
  • Hu, Y.
  • Okerberg, E.
  • Brown, H. E.
  • Pham, L. M.
  • Chung, D. M.
  • Fraser, A. S.
  • McGee, E.
  • Rosenblum, Jonathan
  • Kozarich, J. W.

publication date

  • September 2012

journal

  • Bioorganic & Medicinal Chemistry Letters  Journal

subject areas

  • Animals
  • Carbamates
  • Carboxylic Ester Hydrolases
  • Cell Line, Tumor
  • Enzyme Inhibitors
  • Female
  • Humans
  • Mice
  • Mice, SCID
  • Ovarian Neoplasms
  • Sterol Esterase
  • Structure-Activity Relationship
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Research

keywords

  • Carbamylation
  • KIAA1363 inhibitor
  • Naphthyl carbamate
  • Time-dependent
  • Xenograft
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Identity

International Standard Serial Number (ISSN)

  • 0960-894X

Digital Object Identifier (DOI)

  • 10.1016/j.bmcl.2012.05.102

PubMed ID

  • 22877630
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Additional Document Info

start page

  • 5748

end page

  • 5751

volume

  • 22

issue

  • 17

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