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INCB24360 (epacadostat), a highly potent and selective indoleamine-2,3-dioxygenase 1 (ID01) inhibitor for immunooncology

Academic Article
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Overview

authors

  • Yue, Eddy W
  • Sparks, R.
  • Polam, P.
  • Modi, D.
  • Douty, B.
  • Wayland, B.
  • Glass, B.
  • Takvorian, A.
  • Glenn, J.
  • Zhu, W.
  • Bower, M.
  • Liu, X.
  • Leffet, L.
  • Wang, Q.
  • Bowman, K. J.
  • Hansbury, M. J.
  • Wei, M.
  • Li, Y.
  • Wynn, R.
  • Burn, T. C.
  • Koblish, H. K.
  • Fridman, J. S.
  • Emm, T.
  • Scherle, P. A.
  • Metcalf, B.
  • Combs, A. P.

publication date

  • May 2017

journal

  • ACS Medicinal Chemistry Letters  Journal
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Research

keywords

  • Epacadostat
  • IDO1
  • INCB24360
  • data-centric medicinal chemistry
  • immuno-oncology
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Identity

PubMed Central ID

  • PMC5430407

International Standard Serial Number (ISSN)

  • 1948-5875

Digital Object Identifier (DOI)

  • 10.1021/acsmedchemlett.6b00391

PubMed ID

  • 28523098
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Additional Document Info

start page

  • 486

end page

  • 491

volume

  • 8

issue

  • 5

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