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Discovery of a selective covalent inhibitor of lysophospholipase-like 1 (LYPLAL1) as a tool to evaluate the role of this serine hydrolase in metabolism

Academic Article
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Overview

authors

  • Ahn, K.
  • Boehm, M.
  • Brown, M. F.
  • Calloway, J.
  • Che, Y.
  • Chen, J.
  • Fennell, K. F.
  • Geoghegan, K. F.
  • Gilbert, A. M.
  • Gutierrez, J. A.
  • Kalgutkar, A. S.
  • Lanba, A.
  • Limberalds, C.
  • Magee, T. V.
  • O'Doherty, I.
  • Oliver, R.
  • Pabst, B.
  • Pandit, J.
  • Parris, K.
  • Pfefferkorn, Jeff
  • Rolph, T. P.
  • Patel, R.
  • Schuff, B.
  • Shanmugasundaram, V.
  • Starr, J. T.
  • Varghese, A. H.
  • Vera, N. B.
  • Vernochet, C.
  • Yan, J.

publication date

  • September 2016

journal

  • ACS Chemical Biology  Journal

subject areas

  • Animals
  • Crystallization
  • Crystallography, X-Ray
  • Enzyme Inhibitors
  • Humans
  • Hydrolases
  • Lysophospholipase
  • Serine
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Identity

International Standard Serial Number (ISSN)

  • 1554-8929

Digital Object Identifier (DOI)

  • 10.1021/acschembio.6b00266

PubMed ID

  • 27391855
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Additional Document Info

start page

  • 2529

end page

  • 2540

volume

  • 11

issue

  • 9

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