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T-cell epitope conservation across allergen species is a major determinant of immunogenicity

Academic Article
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  • Research
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Overview

authors

  • Westernberg, Luise Sternberg
  • Schulten, V.
  • Greenbaum, J. A.
  • Natali, S.
  • Tripple, V.
  • McKinney, D. M.
  • Frazier, A.
  • Hofer, H.
  • Wallner, M.
  • Sallusto, F.
  • Sette, A.
  • Peters, B.

publication date

  • August 2016

journal

  • Journal of Allergy and Clinical Immunology  Journal

subject areas

  • Adult
  • Allergens
  • Antigens, Plant
  • Conserved Sequence
  • Cross Reactions
  • Epitopes, T-Lymphocyte
  • Evolution, Molecular
  • Female
  • Gene Expression Profiling
  • Humans
  • Immunoglobulin E
  • Male
  • Middle Aged
  • Poaceae
  • Pollen
  • Rhinitis, Allergic, Seasonal
  • Sequence Analysis, DNA
  • T-Lymphocytes
  • Transcriptome
  • Young Adult
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Research

keywords

  • RNA sequencing
  • T cell
  • cross-reactivity
  • epitope
  • pollen allergy
  • sequence conservation
  • timothy grass allergy
  • transcriptome
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Identity

PubMed Central ID

  • PMC4975972

International Standard Serial Number (ISSN)

  • 0091-6749

Digital Object Identifier (DOI)

  • 10.1016/j.jaci.2015.11.034

PubMed ID

  • 26883464
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Additional Document Info

start page

  • 571

end page

  • 578

volume

  • 138

issue

  • 2

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