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Design and synthesis of 1,2,3-triazole-containing N-acyl zanamivir analogs as potent neuraminidase inhibitors

Academic Article
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Overview

authors

  • Das, A.
  • Adak, A. K.
  • Ponnapalli, K.
  • Lin, C. H.
  • Hsu, K. C.
  • Yang, J. M.
  • Hsu, T. A.
  • Lin, Chun-Cheng

publication date

  • November 2016

journal

  • European Journal of Medicinal Chemistry  Journal

subject areas

  • Antiviral Agents
  • Binding, Competitive
  • Catalytic Domain
  • Chemistry Techniques, Synthetic
  • Drug Design
  • Enzyme Inhibitors
  • Influenza A Virus, H1N1 Subtype
  • Influenza A Virus, H3N2 Subtype
  • Molecular Docking Simulation
  • Molecular Dynamics Simulation
  • Neuraminidase
  • Triazoles
  • Zanamivir
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Research

keywords

  • Influenza
  • Neuraminidase inhibitors
  • Triazole
  • Zanamivir
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Identity

International Standard Serial Number (ISSN)

  • 0223-5234

Digital Object Identifier (DOI)

  • 10.1016/j.ejmech.2016.07.064

PubMed ID

  • 27487569
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Additional Document Info

start page

  • 397

end page

  • 406

volume

  • 123

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