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Druggable Hot Spots in the Schistosomiasis Cathepsin B1 Target Identified by Functional and Binding Mode Analysis of Potent Vinyl Sulfone Inhibitors

Academic Article
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Overview

authors

  • Jilkova, A.
  • Rubesova, P.
  • Fanfrlik, J.
  • Fajtova, P.
  • Rezacova, P.
  • Brynda, J.
  • Lepsik, M.
  • Mertlikova-Kaiserova, H.
  • Emal, C. D.
  • Renslo, A. R.
  • Roush, William
  • Horn, M.
  • Caffrey, C. R.
  • Mares, M.

publication date

  • November 11, 2020

journal

  • Acs Infectious Diseases  Journal

subject areas

  • Animals
  • Cathepsin B
  • Humans
  • Schistosoma mansoni
  • Schistosomiasis
  • Sulfones
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Identity

PubMed Central ID

  • PMC8154419

International Standard Serial Number (ISSN)

  • 2373-8227

Digital Object Identifier (DOI)

  • 10.1021/acsinfecdis.0c00501

PubMed ID

  • 33175511
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Additional Document Info

start page

  • 1077

end page

  • 1088

volume

  • 7

issue

  • 5

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