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Discovery and gram-scale synthesis of BMS-593214, a potent, selective FVIIa inhibitor

Academic Article
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  • Research
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Overview

authors

  • Priestley, E. S.
  • De Lucca, I.
  • Zhou, J. L.
  • Zhou, Jiacheng
  • Saiah, E.
  • Stanton, R.
  • Robinson, L.
  • Luettgen, J. M.
  • Wei, A.
  • Wen, X.
  • Knabb, R. M.
  • Wong, P. C.
  • Wexler, R. R.

publication date

  • April 2013

journal

  • Bioorganic & Medicinal Chemistry Letters  Journal
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Research

keywords

  • Anticoagulant
  • Antithrombotic
  • Benzamidine
  • Coagulation factor VIIa
  • FVIIa
  • Inhibitor
  • Povarov annulation
  • Tetrahydroquinoline
  • Thrombosis
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Identity

International Standard Serial Number (ISSN)

  • 0960-894X

Digital Object Identifier (DOI)

  • 10.1016/j.bmcl.2013.02.013
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Additional Document Info

start page

  • 2432

end page

  • 2435

volume

  • 23

issue

  • 8

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