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Bis(aminopyrrolidine)-derived ureas (APUs) as potent MCH1 receptor antagonists

Academic Article
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  • Overview
  • Research
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Overview

authors

  • Grey, J.
  • Dyck, B.
  • Rowbottom, M. W.
  • Tamiya, Junko
  • Vickers, T. D.
  • Zhang, M.
  • Zhao, L.
  • Heise, C. E.
  • Schwarz, D.
  • Saunders, J.
  • Goodfellow, V. S.

publication date

  • February 2005

journal

  • Bioorganic & Medicinal Chemistry Letters  Journal

subject areas

  • Dose-Response Relationship, Drug
  • Drug Design
  • Humans
  • Pyrrolidines
  • Receptors, Pituitary Hormone
  • Stereoisomerism
  • Structure-Activity Relationship
  • Urea
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Research

keywords

  • anxiety
  • depression
  • melanin-concentrating hormone
  • obesity
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Identity

International Standard Serial Number (ISSN)

  • 0960-894X

Digital Object Identifier (DOI)

  • 10.1016/j.bmcl.2004.12.036

PubMed ID

  • 15686900
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Additional Document Info

start page

  • 999

end page

  • 1004

volume

  • 15

issue

  • 4

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