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Flexibility is important for inhibition of the MDM2/p53 protein-protein interaction by cyclic β-hairpins

Academic Article
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Overview

authors

  • Danelius, E.
  • Pettersson, M.
  • Bred, M.
  • Min, J.
  • Waddell, M. B.
  • Guy, Rodney Kiplin
  • Grotli, M.
  • Erdelyi, M.

publication date

  • 2016

journal

  • Organic & Biomolecular Chemistry  Journal

subject areas

  • Drug Design
  • Models, Molecular
  • Peptidomimetics
  • Protein Binding
  • Protein Conformation, alpha-Helical
  • Proto-Oncogene Proteins c-mdm2
  • Tumor Suppressor Protein p53
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Identity

International Standard Serial Number (ISSN)

  • 1477-0520

Digital Object Identifier (DOI)

  • 10.1039/c6ob01510g

PubMed ID

  • 27731454
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Additional Document Info

start page

  • 10386

end page

  • 10393

volume

  • 14

issue

  • 44

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