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Epothilone C macrolactonization and hydrolysis are catalyzed by the isolated thioesterase domain of epothilone polyketide synthase

Academic Article
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Overview

authors

  • Boddy, Christopher Noyce
  • Schneider, T. L.
  • Hotta, Kinya
  • Walsh, C. T.
  • Khosla, C.

publication date

  • March 2003

journal

  • Journal of the American Chemical Society  Journal

subject areas

  • Catalysis
  • Epothilones
  • Esterases
  • Hydrolysis
  • Lactones
  • Multienzyme Complexes
  • Protein Structure, Tertiary
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Identity

International Standard Serial Number (ISSN)

  • 0002-7863

Digital Object Identifier (DOI)

  • 10.1021/ja0298646

PubMed ID

  • 12643694
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Additional Document Info

start page

  • 3428

end page

  • 3429

volume

  • 125

issue

  • 12

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