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DIx5 homeodomain:DNA complex: structure, binding and effect of mutations related to split hand and foot malformation syndrome

Academic Article
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  • Research
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Overview

authors

  • Proudfoot, A.
  • Axelrod, H. L.
  • Geralt, M.
  • Fletterick, R. J.
  • Yumoto, F.
  • Deacon, A. M.
  • Elsliger, M. A.
  • Wilson, Ian
  • Wuthrich, Kurt
  • Serrano-Navarro, Pedro

publication date

  • March 2016

journal

  • Journal of Molecular Biology  Journal

subject areas

  • Crystallography, X-Ray
  • DNA
  • Homeodomain Proteins
  • Humans
  • Limb Deformities, Congenital
  • Magnetic Resonance Spectroscopy
  • Models, Molecular
  • Mutant Proteins
  • Mutation, Missense
  • Nucleic Acid Conformation
  • Protein Binding
  • Protein Conformation
  • Transcription Factors
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Research

keywords

  • NMR spectroscopy
  • SHFM-1 syndrome
  • protein:DNA complex
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Identity

PubMed Central ID

  • PMC4826628

International Standard Serial Number (ISSN)

  • 0022-2836

Digital Object Identifier (DOI)

  • 10.1016/j.jmb.2016.01.023

PubMed ID

  • 26829219
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Additional Document Info

start page

  • 1130

end page

  • 1141

volume

  • 428

issue

  • 6

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