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Engineered cellular gene-replacement platform for selective and inducible proteolytic profiling

Academic Article
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Overview

authors

  • Morgan, C. W.
  • Diaz, J. E.
  • Zeitlin, Samantha
  • Gray, D. C.
  • Wells, J. A.

publication date

  • July 2015

journal

  • Proceedings of the National Academy of Sciences of the United States of America  Journal

subject areas

  • Apoptosis
  • Apoptosis Regulatory Proteins
  • Caspases
  • Cell Cycle
  • Cell Survival
  • Deoxyribonucleases
  • Flow Cytometry
  • Gene Knockdown Techniques
  • HEK293 Cells
  • HeLa Cells
  • Humans
  • Immunoblotting
  • Mutation
  • Proteolysis
  • Reverse Transcriptase Polymerase Chain Reaction
  • Transfection
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Research

keywords

  • DNA damage
  • ICAD
  • TEV protease
  • apoptosis
  • site-specific proteolysis
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Identity

PubMed Central ID

  • PMC4500269

International Standard Serial Number (ISSN)

  • 0027-8424

Digital Object Identifier (DOI)

  • 10.1073/pnas.1504141112

PubMed ID

  • 26106156
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Additional Document Info

start page

  • 8344

end page

  • 8349

volume

  • 112

issue

  • 27

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