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Lysine-specific demethylase 1-selective inactivators: protein-targeted drug delivery mechanism

Academic Article
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Overview

authors

  • Ogasawara, Daisuke
  • Itoh, Y.
  • Tsumoto, H.
  • Kakizawa, T.
  • Mino, K.
  • Fukuhara, K.
  • Nakagawa, H.
  • Hasegawa, M.
  • Sasaki, R.
  • Mizukami, T.
  • Miyata, N.
  • Suzuki, T.

publication date

  • August 2013

journal

  • Angewandte Chemie - International Edition  Journal

subject areas

  • Catalytic Domain
  • Crystallography, X-Ray
  • Drug Delivery Systems
  • Enzyme Inhibitors
  • Flavin-Adenine Dinucleotide
  • Histone Demethylases
  • Humans
  • Lysine
  • Molecular Structure
  • Monoamine Oxidase
  • Monoamine Oxidase Inhibitors
  • Peptide Fragments
  • Small Molecule Libraries
  • Tranylcypromine
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Research

keywords

  • biological activity
  • drug delivery
  • drug design
  • kinetics
  • proteins
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Identity

International Standard Serial Number (ISSN)

  • 1433-7851

Digital Object Identifier (DOI)

  • 10.1002/anie.201303999

PubMed ID

  • 23824985
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Additional Document Info

start page

  • 8620

end page

  • 8624

volume

  • 52

issue

  • 33

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