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Discovery of potent and selective inhibitors of Trypanosoma brucei ornithine decarboxylase

Academic Article
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Overview

authors

  • Smithson, D. C.
  • Lee, J.
  • Shelat, A. A.
  • Phillips, M. A.
  • Guy, Rodney Kiplin

publication date

  • 2010

journal

  • Journal of Biological Chemistry  Journal

subject areas

  • Allosteric Site
  • Animals
  • Automation
  • Chemistry, Pharmaceutical
  • Drug Design
  • Enzyme Inhibitors
  • Humans
  • Malate Dehydrogenase
  • Mutagenesis, Site-Directed
  • Ornithine Decarboxylase Inhibitors
  • Phosphoenolpyruvate Carboxylase
  • Protein Binding
  • Trypanocidal Agents
  • Trypanosoma brucei brucei
  • Trypanosomiasis, African
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Identity

PubMed Central ID

  • PMC2878083

International Standard Serial Number (ISSN)

  • 0021-9258

Digital Object Identifier (DOI)

  • 10.1074/jbc.M109.081588

PubMed ID

  • 20220141
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Additional Document Info

start page

  • 16771

end page

  • 16781

volume

  • 285

issue

  • 22

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