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Opposing functions of the T cell receptor kinase ZAP-70 in immunity and tolerance differentially titrate in response to nucleotide substitutions

Academic Article
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Overview

authors

  • Siggs, Owen Marc
  • Miosge, L. A.
  • Yates, A. L.
  • Kucharska, E. M.
  • Sheahan, D.
  • Brdicka, T.
  • Weiss, A.
  • Liston, A.
  • Goodnow, C. C.

publication date

  • December 2007

journal

  • Immunity  Journal

subject areas

  • Amino Acid Substitution
  • Animals
  • Autoantibodies
  • Immune Tolerance
  • Immunity
  • Immunoglobulin E
  • Immunoglobulin G
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Receptors, Antigen, T-Cell
  • Signal Transduction
  • Structure-Activity Relationship
  • T-Lymphocytes, Helper-Inducer
  • ZAP-70 Protein-Tyrosine Kinase
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Identity

PubMed Central ID

  • PMC3163119

International Standard Serial Number (ISSN)

  • 1074-7613

Digital Object Identifier (DOI)

  • 10.1016/j.immuni.2007.11.013

PubMed ID

  • 18093540
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Additional Document Info

start page

  • 912

end page

  • 926

volume

  • 27

issue

  • 6

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