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Synthesis and biological evaluation of manassantin analogues for hypoxia-inducible factor 1α inhibition

Academic Article
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Overview

authors

  • Kwon, D. Y.
  • Lee, H. E.
  • Weitzel, D. H.
  • Park, K.
  • Lee, S. H.
  • Lee, C. T.
  • Stephenson, T. N.
  • Park, H.
  • Fitzgerald, M. C.
  • Chi, J. T.
  • Mook Jr., R. A.
  • Dewhirst, M. W.
  • Lee, Y. M.
  • Hong, Jiyong

publication date

  • October 2015

journal

  • Journal of Medicinal Chemistry  Journal

subject areas

  • Chemistry Techniques, Synthetic
  • Cross-Linking Reagents
  • Drug Evaluation, Preclinical
  • Gene Expression Regulation
  • HEK293 Cells
  • Humans
  • Hypoxia-Inducible Factor 1, alpha Subunit
  • Inhibitory Concentration 50
  • Lignans
  • Molecular Structure
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Identity

PubMed Central ID

  • PMC4765894

International Standard Serial Number (ISSN)

  • 0022-2623

Digital Object Identifier (DOI)

  • 10.1021/acs.jmedchem.5b01220

PubMed ID

  • 26394152
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Additional Document Info

start page

  • 7659

end page

  • 7671

volume

  • 58

issue

  • 19

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