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A single glycine in extracellular loop 1 is the critical determinant for pharmacological specificity of dopamine D2 and D3 receptors

Academic Article
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  • Identity
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Overview

authors

  • Michino, Mayako
  • Donthamsetti, P.
  • Beuming, T.
  • Banala, A.
  • Duan, L.
  • Roux, T.
  • Han, Y.
  • Trinquet, E.
  • Newman, A. H.
  • Javitch, J. A.
  • Shi, L.

publication date

  • 2013

journal

  • Molecular Pharmacology  Journal

subject areas

  • Binding Sites
  • Binding, Competitive
  • Glycine
  • HEK293 Cells
  • Humans
  • Ligands
  • Molecular Docking Simulation
  • Molecular Dynamics Simulation
  • Mutagenesis, Site-Directed
  • Piperazines
  • Protein Conformation
  • Radioligand Assay
  • Receptors, Dopamine D2
  • Receptors, Dopamine D3
  • Recombinant Fusion Proteins
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Identity

PubMed Central ID

  • PMC3834143

International Standard Serial Number (ISSN)

  • 0026-895X

Digital Object Identifier (DOI)

  • 10.1124/mol.113.087833

PubMed ID

  • 24061855
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Additional Document Info

start page

  • 854

end page

  • 864

volume

  • 84

issue

  • 6

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