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Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry

Academic Article
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Overview

authors

  • Durbin, A. D.
  • Zimmerman, M. W.
  • Dharia, Neekesh
  • Abraham, B. J.
  • Iniguez, A. B.
  • Weichert-Leahey, N.
  • He, S.
  • Krill-Burger, J. M.
  • Root, D. E.
  • Vazquez, F.
  • Tsherniak, A.
  • Hahn, W. C.
  • Golub, T. R.
  • Young, R. A.
  • Look, A. T.
  • Stegmaier, K.

publication date

  • September 2018

journal

  • Nature Genetics  Journal

subject areas

  • Animals
  • CRISPR-Cas Systems
  • Cell Line, Tumor
  • Disease Models, Animal
  • Down-Regulation
  • Female
  • Gene Amplification
  • Gene Expression Regulation, Neoplastic
  • Humans
  • Mice
  • Mice, Nude
  • N-Myc Proto-Oncogene Protein
  • Neuroblastoma
  • Transcription Factors
  • Transcription, Genetic
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Identity

PubMed Central ID

  • PMC6386470

International Standard Serial Number (ISSN)

  • 1061-4036

Digital Object Identifier (DOI)

  • 10.1038/s41588-018-0191-z

PubMed ID

  • 30127528
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Additional Document Info

start page

  • 1240

end page

  • 1246

volume

  • 50

issue

  • 9

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