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Correcting the F508del-CFTR variant by modulating eukaryotic translation initiation factor 3-mediated translation initiation

Academic Article
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Overview

authors

  • Hutt, D. M.
  • Loguercio, S.
  • Roth, D. M.
  • Su, Andrew
  • Balch, William E.

publication date

  • 2018

journal

  • Journal of Biological Chemistry  Journal
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Research

keywords

  • F508del-CFTR
  • cystic fibrosis
  • cystic fibrosis transmembrane conductance regulator (CFTR)
  • eIF3a
  • eukaryotic translation initiation
  • eukaryotic translation initiation factor 3
  • network hub
  • protein misfolding
  • protein translation
  • proteostasis
  • translation initiation factor
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Identity

PubMed Central ID

  • PMC6120211

International Standard Serial Number (ISSN)

  • 0021-9258

Digital Object Identifier (DOI)

  • 10.1074/jbc.RA118.003192

PubMed ID

  • 30006345
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Additional Document Info

start page

  • 13477

end page

  • 13495

volume

  • 293

issue

  • 35

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