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Impairment of chaperone-mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosis

Academic Article
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Overview

authors

  • Napolitano, G.
  • Johnson, J. L.
  • He, J.
  • Rocca, C. J.
  • Monfregola, J.
  • Pestonjamasp, K.
  • Cherqui, Stephanie
  • Catz, Sergio

publication date

  • February 2015

journal

  • EMBO Molecular Medicine  Journal

subject areas

  • Amino Acid Transport Systems, Neutral
  • Animals
  • Autophagy
  • Cystine
  • Cystinosis
  • Humans
  • Lysosomal-Associated Membrane Protein 2
  • Lysosomes
  • Mice
  • Mice, Inbred C57BL
  • Mice, Knockout
  • Molecular Chaperones
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Research

keywords

  • CTNS
  • autophagy
  • cystinosis
  • lysosomal storage disorder
  • lysosomal trafficking
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Identity

PubMed Central ID

  • PMC4328646

International Standard Serial Number (ISSN)

  • 1757-4676

Digital Object Identifier (DOI)

  • 10.15252/emmm.201404223

PubMed ID

  • 25586965
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Additional Document Info

start page

  • 158

end page

  • 174

volume

  • 7

issue

  • 2

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