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Determination of unbound antiretroviral drug concentrations by a modified ultrafiltration method reveals high variability in the free fraction

Academic Article
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Overview

authors

  • Fayet, A.
  • Beguin, A.
  • de Tejada, B. M.
  • Colombo, S.
  • Cavassini, M.
  • Gerber, S.
  • Eap, C. B.
  • Telenti, Amalio
  • Buclin, T.
  • Biollaz, J.
  • Decosterd, L. A.

publication date

  • August 2008

journal

  • Therapeutic Drug Monitoring  Journal

subject areas

  • Anti-HIV Agents
  • Antiretroviral Therapy, Highly Active
  • Calibration
  • Chromatography, High Pressure Liquid
  • Glycated Hemoglobin A
  • HIV Infections
  • Humans
  • Indicators and Reagents
  • Quality Control
  • Serum Albumin
  • Tandem Mass Spectrometry
  • Ultrafiltration
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Research

keywords

  • LC-MS/MS
  • antiretroviral drugs
  • free concentrations
  • protein binding
  • therapeutic drug monitoring
  • ultrafiltration
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Identity

International Standard Serial Number (ISSN)

  • 0163-4356

PubMed ID

  • 18641538
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Additional Document Info

start page

  • 511

end page

  • 522

volume

  • 30

issue

  • 4

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