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Inhibition of phosphodiesterase 2 increases neuronal cGMP, synaptic plasticity and memory performance

Academic Article
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  • Research
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Overview

authors

  • Boess, F. G.
  • Hendrix, Martin
  • van der Staay, F. J.
  • Erb, C.
  • Schreiber, R.
  • van Staveren, W.
  • de Vente, J.
  • Prickaerts, J.
  • Blokland, A.
  • Koenig, G.

publication date

  • December 2004

journal

  • Neuropharmacology  Journal

subject areas

  • Animals
  • CHO Cells
  • Cattle
  • Cricetinae
  • Cyclic AMP
  • Cyclic GMP
  • Exonucleases
  • Guinea Pigs
  • Hippocampus
  • Humans
  • Immunohistochemistry
  • Long-Term Potentiation
  • Male
  • Maze Learning
  • Memory
  • Mice
  • Mice, Inbred C57BL
  • Neuronal Plasticity
  • Neurons
  • Phosphodiesterase Inhibitors
  • Psychomotor Performance
  • Rats
  • Rats, Wistar
  • Recombinant Proteins
  • Signal Transduction
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Research

keywords

  • LTP
  • PDE2
  • cGMP
  • learning
  • long-term potentiation
  • memory
  • phosphodiesterase 2
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Identity

International Standard Serial Number (ISSN)

  • 0028-3908

Digital Object Identifier (DOI)

  • 10.1016/j.neuropharm.2004.07.040

PubMed ID

  • 15555642
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Additional Document Info

start page

  • 1081

end page

  • 1092

volume

  • 47

issue

  • 7

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