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CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma

Academic Article
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  • Research
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Overview

authors

  • Huang, C. H.
  • Lujambio, A.
  • Zuber, J.
  • Tschaharganeh, D. F.
  • Doran, M. G.
  • Evans, Michael
  • Kitzing, T.
  • Zhu, N.
  • de Stanchina, E.
  • Sawyers, C. L.
  • Armstrong, S. A.
  • Lewis, J. S.
  • Sherr, C. J.
  • Lowe, S. W.

publication date

  • August 2014

journal

  • Genes & Development  Journal

subject areas

  • Animals
  • Carcinoma, Hepatocellular
  • Cell Line, Tumor
  • Cell Proliferation
  • Cyclin-Dependent Kinase 9
  • Female
  • Gene Expression
  • Gene Library
  • Hep G2 Cells
  • Humans
  • Liver Neoplasms
  • Mice
  • Positive Transcriptional Elongation Factor B
  • Proto-Oncogene Proteins c-myc
  • RNA Interference
  • RNA, Small Interfering
  • Transcription Elongation, Genetic
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Research

keywords

  • CDK9
  • MYC
  • RNAi screen
  • oncogene addiction
  • transcription elongation
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Identity

PubMed Central ID

  • PMC4197965

International Standard Serial Number (ISSN)

  • 0890-9369

Digital Object Identifier (DOI)

  • 10.1101/gad.244368.114

PubMed ID

  • 25128497
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Additional Document Info

start page

  • 1800

end page

  • 1814

volume

  • 28

issue

  • 16

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