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Targeting AKT with the proapoptotic peptide, TAT-CTMP: A novel strategy for the treatment of human pancreatic adenocarcinoma

Academic Article
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Overview

authors

  • Simon, P. O.
  • McDunn, Jonathan
  • Kashiwagi, H.
  • Chang, K.
  • Goedegebuure, P. S.
  • Hotchkiss, R. S.
  • Hawkins, W. G.

publication date

  • August 2009

journal

  • International Journal of Cancer  Journal

subject areas

  • Adaptor Proteins, Signal Transducing
  • Adenocarcinoma
  • Animals
  • Antimetabolites, Antineoplastic
  • Apoptosis
  • Blotting, Western
  • Caspases
  • Deoxycytidine
  • Drug Resistance, Neoplasm
  • Female
  • Flow Cytometry
  • Humans
  • Immunoblotting
  • Immunoenzyme Techniques
  • In Situ Nick-End Labeling
  • Membrane Proteins
  • Mice
  • Mice, Inbred C57BL
  • Mice, Nude
  • Pancreatic Neoplasms
  • Peptide Fragments
  • Phosphorylation
  • Proto-Oncogene Proteins c-akt
  • Radiation Tolerance
  • Thiolester Hydrolases
  • Tumor Cells, Cultured
  • Xenograft Model Antitumor Assays
  • tat Gene Products, Human Immunodeficiency Virus
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Research

keywords

  • AKT
  • CTMP
  • apoptosis
  • pancreas cancer
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Identity

PubMed Central ID

  • PMC3645501

International Standard Serial Number (ISSN)

  • 0020-7136

Digital Object Identifier (DOI)

  • 10.1002/ijc.24424

PubMed ID

  • 19405118
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Additional Document Info

start page

  • 942

end page

  • 951

volume

  • 125

issue

  • 4

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