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Modulation of cofilin phosphorylation by inhibition of the Lim family kinases

Academic Article
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Overview

authors

  • He, L.
  • Seitz, S. P.
  • Trainor, G. L.
  • Tortolani, D.
  • Vaccaro, W.
  • Poss, M.
  • Tarby, Christine
  • Tokarski, J. S.
  • Penhallow, B.
  • Hung, C. Y.
  • Attar, R.
  • Lin, T. A.

publication date

  • September 2012

journal

  • Bioorganic & Medicinal Chemistry Letters  Journal

subject areas

  • Actin Depolymerizing Factors
  • Cell Line
  • Crystallography, X-Ray
  • Dose-Response Relationship, Drug
  • Humans
  • Lim Kinases
  • Models, Molecular
  • Molecular Structure
  • Phosphorylation
  • Protein Kinase Inhibitors
  • Structure-Activity Relationship
  • Thiazoles
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Research

keywords

  • Actin cytoskeleton
  • Cofilin phosphorylation
  • LIMK1
  • LIMK2
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Identity

International Standard Serial Number (ISSN)

  • 0960-894X

Digital Object Identifier (DOI)

  • 10.1016/j.bmcl.2012.07.002

PubMed ID

  • 22902653
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Additional Document Info

start page

  • 5995

end page

  • 5998

volume

  • 22

issue

  • 18

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