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Enediynes: Exploration of microbial genomics to discover new anticancer drug leads

Academic Article
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Overview

authors

  • Shen, Ben
  • Hindra, F.
  • Yan, X.
  • Huang, T.
  • Ge, H.
  • Yang, D.
  • Teng, Q.
  • Rudolf, J. D.
  • Lohman, J. R.

publication date

  • January 2015

journal

  • Bioorganic & Medicinal Chemistry Letters  Journal

subject areas

  • Animals
  • Antineoplastic Agents
  • Drug Discovery
  • Enediynes
  • Genome, Microbial
  • Genomics
  • Humans
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Research

keywords

  • ADC payload
  • Biosynthetic gene cluster
  • Enediyne polyketide synthase
  • Genome mining
  • Natural products
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Identity

PubMed Central ID

  • PMC4480864

International Standard Serial Number (ISSN)

  • 0960-894X

Digital Object Identifier (DOI)

  • 10.1016/j.bmcl.2014.11.019

PubMed ID

  • 25434000
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Additional Document Info

start page

  • 9

end page

  • 15

volume

  • 25

issue

  • 1

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