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Importance of single molecular determinants in the fidelity of expanded genetic codes

Academic Article
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Overview

authors

  • Antonczak, A. K.
  • Simova, Z.
  • Yonemoto, Isaac Takashi
  • Bochtler, M.
  • Piasecka, A.
  • Czapinska, H.
  • Brancale, A.
  • Tippmann, E. M.

publication date

  • January 2011

journal

  • Proceedings of the National Academy of Sciences of the United States of America  Journal

subject areas

  • Amino Acids
  • Amino Acyl-tRNA Synthetases
  • Anticodon
  • Base Sequence
  • Calorimetry
  • Crystallography, X-Ray
  • Genetic Code
  • Hydrogen Bonding
  • Methanococcales
  • Models, Molecular
  • Molecular Sequence Data
  • Molecular Structure
  • Mutation
  • Protein Binding
  • Protein Structure, Tertiary
  • RNA, Transfer, Tyr
  • Substrate Specificity
  • Tyrosine
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Research

keywords

  • directed evolution
  • protein engineering
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Identity

PubMed Central ID

  • PMC3029751

International Standard Serial Number (ISSN)

  • 0027-8424

Digital Object Identifier (DOI)

  • 10.1073/pnas.1012276108

PubMed ID

  • 21224416
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Additional Document Info

start page

  • 1320

end page

  • 1325

volume

  • 108

issue

  • 4

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