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HDX reveals unique fragment ligands for the vitamin D receptor

Academic Article
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Overview

authors

  • Carson, M. W.
  • Zhang, J.
  • Chalmers, Michael
  • Bocchinfuso, W. P.
  • Holifield, K. D.
  • Masquelin, T.
  • Stites, R. E.
  • Stayrook, K. R.
  • Griffin, Patrick
  • Dodge, J. A.

publication date

  • August 2014

journal

  • Bioorganic & Medicinal Chemistry Letters  Journal

subject areas

  • Deuterium Exchange Measurement
  • Dose-Response Relationship, Drug
  • Drug Design
  • Ligands
  • Mass Spectrometry
  • Models, Molecular
  • Molecular Structure
  • Organic Chemicals
  • Receptors, Calcitriol
  • Structure-Activity Relationship
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Research

keywords

  • Fragment based drug design
  • Hydrogen-deuterium exchange
  • Vitamin D receptor
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Identity

International Standard Serial Number (ISSN)

  • 0960-894X

Digital Object Identifier (DOI)

  • 10.1016/j.bmcl.2014.05.070

PubMed ID

  • 24974344
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Additional Document Info

start page

  • 3459

end page

  • 3463

volume

  • 24

issue

  • 15

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