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alpha-Ketoheterocycle inhibitors of fatty acid amide hydrolase: exploration of conformational constraints in the acyl side chain

Academic Article
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Overview

related to degree

  • Duncan, Katharine, Ph.D. in Chemistry, Scripps Research 2008 - 2014

authors

  • Duncan, Katharine
  • Otrubova, Katerina
  • Boger, Dale

publication date

  • May 2014

journal

  • Bioorganic & Medicinal Chemistry  Journal

subject areas

  • Amidohydrolases
  • Animals
  • Brain
  • Crystallography, X-Ray
  • Enzyme Inhibitors
  • Mice
  • Molecular Conformation
  • Oxazoles
  • Proteome
  • Stereoisomerism
  • Tetrahydronaphthalenes
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Research

keywords

  • Fatty acid amide hydrolase
  • alpha-Ketoheterocycles
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Identity

PubMed Central ID

  • PMC4029506

International Standard Serial Number (ISSN)

  • 0968-0896

Digital Object Identifier (DOI)

  • 10.1016/j.bmc.2014.03.013

PubMed ID

  • 24690529
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Additional Document Info

start page

  • 2763

end page

  • 2770

volume

  • 22

issue

  • 9

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