recent publications

• academic article

  • Wang, J., Shanmugam, A., Markand, S., Zorrilla, E., Ganapathy, V., Smith, S. B. Sigma 1 receptor regulates the oxidative stress response in primary retinal Müller glial cells via NRF2 signaling and system xc(-), the Na(+)-independent glutamate-cystine exchanger Free Radical Biology and Medicine  2015 86:25-36  DOI:10.1016/j.freeradbiomed.2015.04.009  PMID:25920363  PMCID:PMC4554890
  • Shanmugam, A., Wang, J., Markand, S., Perry, R. L., Tawfik, A., Zorrilla, E., Ganapathy, V., Smith, S. B. Sigma receptor 1 activation attenuates release of inflammatory cytokines MIP1 gamma, MIP2, MIP3 alpha, and IL12 (p40/p70) by retinal Muller glial cells Journal of Neurochemistry  2015 132:546-558  DOI:10.1111/jnc.13002  PMID:25439327  PMCID:PMC4451448
  • Ha, Y. J., Shanmugam, A. K., Markand, S., Zorrilla, E., Ganapathy, V., Smith, S. B. Sigma receptor 1 modulates ER stress and Bcl2 in murine retina Cell and Tissue Research  2014 356:15-27  DOI:10.1007/s00441-013-1774-8  PMID:24469320  PMCID:PMC3976706