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Disruption of the plasminogen activator inhibitor-1 gene reduces the adiposity and improves the metabolic profile of genetically obese and diabetic ob/ob mice

Academic Article
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  • Overview
  • Research
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Overview

authors

  • Schafer, K.
  • Fujisawa, K.
  • Konstantinides, S.
  • Loskutoff, David J.

publication date

  • June 2001

journal

  • FASEB Journal  Journal

subject areas

  • Adipose Tissue
  • Animals
  • Body Composition
  • Diabetes Mellitus
  • Gene Expression
  • Hyperglycemia
  • Hyperinsulinism
  • Mice
  • Mice, Inbred C57BL
  • Mice, Knockout
  • Mice, Obese
  • Obesity
  • Plasminogen Activator Inhibitor 1
  • Tumor Necrosis Factor-alpha
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Research

keywords

  • animal models
  • gene disruption
  • insulin resistance
  • obesity
  • tumor necrosis factor alpha
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Identity

International Standard Serial Number (ISSN)

  • 0892-6638

Digital Object Identifier (DOI)

  • 10.1096/fj.00-0750fje

PubMed ID

  • 11481248
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Additional Document Info

start page

  • 1840

end page

  • 1842

volume

  • 15

issue

  • 10

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