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Xue, Song
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Xue, Song

Graduate Student
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Positions

  • 2018 - Faculty Member, Beijing University of Chemical Technology
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Publications

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  • academic article

    • degree-related publication Kallupi, M., Xue, S., Zhou, B., Janda, K. D., George, O. An enzymatic approach reverses nicotine dependence, decreases compulsive-like intake, and prevents relapse Science Advances  2018 4  DOI:10.1126/sciadv.aat4751  PMID:30345354  PMCID:PMC6192681
    • degree-related publication Tararina, M. A., Xue, S., Smith, L. C., Muellers, S. N., Miranda, P. O., Janda, K. D., Allen, K. N. Crystallography coupled with kinetic analysis provides mechanistic underpinnings of a nicotine-degrading enzyme Biochemistry  2018 57:3741-3751  DOI:10.1021/acs.biochem.8b00384  PMID:29812904
    • degree-related publication Xue, S., Kallupi, M., Zhou, B., Smith, L. C., Miranda, P. O., George, O., Janda, K. D. An enzymatic advance in nicotine cessation therapy Chemical Communications  2018 54:1686-1689  DOI:10.1039/c7cc09134f  PMID:29308799
    • degree-related publication Xue, S., Seki, H., Remes, M., Silhar, P., Janda, K. Examination of α-exosite inhibitors against Botulinum neurotoxin A protease through structure-activity relationship studies of chicoric acid Bioorganic & Medicinal Chemistry Letters  2017 27:4956-4959  DOI:10.1016/j.bmcl.2017.10.021  PMID:29050781  PMCID:PMC5667901
    • degree-related publication Seki, H., Xue, S., Pellet, S., Silhar, P., Johnson, E. A., Janda, K. D. Cellular protection of SNAP-25 against botulinum neurotoxin/A: inhibition of thioredoxin reductase through a suicide substrate mechanism Journal of the American Chemical Society  2016 138:5568-5575  DOI:10.1021/jacs.5b12929  PMID:27070533  PMCID:PMC4881748
    • degree-related publication Bremer, P. T., Xue, S., Janda, K. D. Picolinic acids as β-exosite inhibitors of botulinum neurotoxin A light chain Chemical Communications  2016 52:12521-12524  DOI:10.1039/c6cc06749b  PMID:27722252  PMCID:PMC5085802
    • degree-related publication Sue, S., Schlosburg, J. E., Janda, K. D. A new strategy for smoking cessation: characterization of a bacterial enzyme for the degradation of nicotine Journal of the American Chemical Society  2015 137:10136-10139  DOI:10.1021/jacs.5b06605  PMID:26237398
    • degree-related publication Seki, H., Xue, S., Hixon, M. S., Pellett, S., Remes, M., Johnson, E. A., Janda, K. D. Toward the discovery of dual inhibitors for botulinum neurotoxin A: concomitant targeting of endocytosis and light chain protease activity Chemical Communications  2015 51:6226-6229  DOI:10.1039/c5cc00677e  PMID:25759983
    • degree-related publication Xue, S., Javor, S., Hixon, M. S., Janda, K. D. Probing BoNT/A protease exosites: implications for inhibitor design and light chain longevity Biochemistry  2014 53:6820-6824  DOI:10.1021/bi500950x  PMID:25295706  PMCID:PMC4222541
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Background

education and training

  • Ph.D. in Chemical Biology, Scripps Research 2013 - 2018
  • B.S. in Chemistry, Tsinghua University 2008 - 2012

advisee of

  • graduate advising relationship

    • Janda, Kim, Ph.D.  candidacy, 2014 - 2018
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Contact

full name

  • Song Xue

geographic location

  • Scripps California 

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