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Whitmire, Jason
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Whitmire, Jason

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Positions

  • - 2010 Assistant Professor, Immunology and Microbial Science (IMS) , Scripps Research
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Publications

recent publications

  • academic article

    • Misumi, I., Alirezaei, M., Eam, B., Su, M. A., Whitton, J. L., Whitmire, J. K. Differential T cell responses to residual viral antigen prolong CD4(+) T cell contraction following the resolution of infection Journal of Immunology  2013 191:5655-5668  DOI:10.4049/jimmunol.1301215  PMID:24146043  PMCID:PMC3879805
    • Botten, J., Whitton, J. L., Barrowman, P., Sidney, J., Whitmire, J. K., Alexander, J., Kotturi, M. F., Sette, A., Buchmeier, M. J. A multivalent vaccination strategy for the prevention of old world arenavirus infection in humans Journal of Virology  2010 84:9947-9956  DOI:10.1128/jvi.00672-10  PMID:20668086  PMCID:PMC2937778
    • Kemball, C. C., Harkins, S., Whitmire, J. K., Flynn, C. T., Feuer, R., Whitton, J. L. Coxsackievirus b3 inhibits antigen presentation in vivo, exerting a profound and selective effect on the mhc class i pathway PLoS Pathogens  2009 5:e1000618  DOI:10.1371/journal.ppat.1000618  PMID:19834548  PMCID:PMC2757675
    • Whitmire, J. K., Eam, B., Whitton, J. L. Mice deficient in stem cell antigen-1 (sca1, ly-6a/e) develop normal primary and memory cd4(+) and cd8(+) t-cell responses to virus infection European Journal of Immunology  2009 39:1494-1504  DOI:10.1002/eji.200838959  PMID:19384870  PMCID:PMC2757104
    • Whitmire, J. K., Benning, N., Eam, B., Whitton, J. L. Increasing the CD4+ T cell precursor frequency leads to competition for IFN-gamma thereby degrading memory cell quantity and quality Journal of Immunology  2008 180:6777-6785  PMID:18453598  PMCID:PMC2788825
    • Whitmire, J. K., Eam, B., Whitton, J. L. Tentative t cells: Memory cells are quick to respond, but slow to divide PLoS Pathogens  2008 4:e1000041  DOI:10.1371/journal.ppat.1000041  PMID:18404208  PMCID:PMC2275797
    • Iannacone, M., Sitia, G., Isogawa, M., Whitmire, J. K., Marchese, P., Chisari, F. V., Ruggeri, Z. M., Guidotti, L. G. Platelets prevent IFN-α/β-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus Proceedings of the National Academy of Sciences of the United States of America  2008 105:629-634  DOI:10.1073/pnas.0711200105  PMID:18184798  PMCID:PMC2206587
    • Crocker, S. J., Frausto, R. F., Whitmire, J. K., Benning, N., Milner, R., Whitton, J. L. Amelioration of coxsackievirus b3-mediated myocarditis by inhibition of tissue inhibitors of matrix metalloproteinase-1 American Journal of Pathology  2007 171:1762-1773  DOI:10.2353/ajpath.2007.070179  PMID:18055551  PMCID:PMC2111101
    • Frausto, R. F., Crocker, S. J., Earn, B., Whitmire, J. K., Whitton, J. L. Myelin oligodendrocyte glycoprotein peptide-induced experimental allergic encephalomyelitis and t cell responses are unaffected by immunoproteasome deficiency Journal of Neuroimmunology  2007 192:124-133  DOI:10.1016/j.jneuroim.2007.09.024  PMID:17964666  PMCID:PMC2175388
    • Whitmire, J. K., Eam, B., Benning, N., Whitton, J. L. Direct interferon-gamma signalling and cd8(+) t cell memory Journal of Immunology  2007 179:1190-1197  PMID:17617612
    • Botten, J., Whitton, J. L., Barrowman, P., Sidney, J., Whitmire, J. K., Alexander, J., Ting, J. P. C., Bui, H. H., Sette, A., Buchmeier, M. J. Hla-a2-restricted protection against lethal lymphocytic choriomeningitis Journal of Virology  2007 81:2307-2317  DOI:10.1128/jvi.02063-06  PMID:17166907
    • Crocker, S. J., Whitmire, J. K., Frausto, R. F., Chertboonmuang, P., Soloway, P. D., Whitton, J. L., Campbell, I. L. Persistent macrophage/microglial activation and myelin disruption after experimental autoimmune encephalomyelitis in tissue inhibitor of metalloproteinase-1-deficient mice American Journal of Pathology  2006 169:2104-2116  DOI:10.2353/ajpath.2006.060626  PMID:17148673  PMCID:PMC1762490
    • Whitmire, J. K., Benning, N., Whitton, J. L. Precursor frequency, nonlinear proliferation, and functional maturation of virus-specific CD4(+) T cells Journal of Immunology  2006 176:3028-3036  PMID:16493061
    • Whitmire, J. K., Benning, N., Whitton, J. L. Cutting edge: Early ifn-gamma signaling directly enhances primary antivliwal cd4(+) t cell responses Journal of Immunology  2005 175:5624-5628  PMID:16237051
    • Whitmire, J. K., Tan, J. T., Whitton, J. L. Interferon-gamma acts directly on cd8(+) t cells to increase their abundance during virus infection Journal of Experimental Medicine  2005 201:1053-1059  DOI:10.1084/jem.20041463  PMID:15809350  PMCID:PMC2213135
    • Whitton, J. L., Slifka, M. K., Nussbaum, A. K., Whitmire, J. K., Liu, F. The regulation and maturation of antiviral immune responses Advances in Virus Research  2004 63:181-238  DOI:10.1016/s0065-3527(04)63003-x  PMID:15530562
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  • Jason K. Whitmire

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