recent publications
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academic article
- Misumi, I., Alirezaei, M., Eam, B., Su, M. A., Whitton, J. L., Whitmire, J. K. Differential T cell responses to residual viral antigen prolong CD4(+) T cell contraction following the resolution of infection Journal of Immunology 2013 191:5655-5668 DOI:10.4049/jimmunol.1301215 PMID:24146043 PMCID:PMC3879805
- Botten, J., Whitton, J. L., Barrowman, P., Sidney, J., Whitmire, J. K., Alexander, J., Kotturi, M. F., Sette, A., Buchmeier, M. J. A multivalent vaccination strategy for the prevention of old world arenavirus infection in humans Journal of Virology 2010 84:9947-9956 DOI:10.1128/jvi.00672-10 PMID:20668086 PMCID:PMC2937778
- Kemball, C. C., Harkins, S., Whitmire, J. K., Flynn, C. T., Feuer, R., Whitton, J. L. Coxsackievirus b3 inhibits antigen presentation in vivo, exerting a profound and selective effect on the mhc class i pathway PLoS Pathogens 2009 5:e1000618 DOI:10.1371/journal.ppat.1000618 PMID:19834548 PMCID:PMC2757675
- Whitmire, J. K., Eam, B., Whitton, J. L. Mice deficient in stem cell antigen-1 (sca1, ly-6a/e) develop normal primary and memory cd4(+) and cd8(+) t-cell responses to virus infection European Journal of Immunology 2009 39:1494-1504 DOI:10.1002/eji.200838959 PMID:19384870 PMCID:PMC2757104
- Whitmire, J. K., Benning, N., Eam, B., Whitton, J. L. Increasing the CD4+ T cell precursor frequency leads to competition for IFN-gamma thereby degrading memory cell quantity and quality Journal of Immunology 2008 180:6777-6785 PMID:18453598 PMCID:PMC2788825
- Whitmire, J. K., Eam, B., Whitton, J. L. Tentative t cells: Memory cells are quick to respond, but slow to divide PLoS Pathogens 2008 4:e1000041 DOI:10.1371/journal.ppat.1000041 PMID:18404208 PMCID:PMC2275797
- Iannacone, M., Sitia, G., Isogawa, M., Whitmire, J. K., Marchese, P., Chisari, F. V., Ruggeri, Z. M., Guidotti, L. G. Platelets prevent IFN-α/β-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus Proceedings of the National Academy of Sciences of the United States of America 2008 105:629-634 DOI:10.1073/pnas.0711200105 PMID:18184798 PMCID:PMC2206587
- Crocker, S. J., Frausto, R. F., Whitmire, J. K., Benning, N., Milner, R., Whitton, J. L. Amelioration of coxsackievirus b3-mediated myocarditis by inhibition of tissue inhibitors of matrix metalloproteinase-1 American Journal of Pathology 2007 171:1762-1773 DOI:10.2353/ajpath.2007.070179 PMID:18055551 PMCID:PMC2111101
- Frausto, R. F., Crocker, S. J., Earn, B., Whitmire, J. K., Whitton, J. L. Myelin oligodendrocyte glycoprotein peptide-induced experimental allergic encephalomyelitis and t cell responses are unaffected by immunoproteasome deficiency Journal of Neuroimmunology 2007 192:124-133 DOI:10.1016/j.jneuroim.2007.09.024 PMID:17964666 PMCID:PMC2175388
- Whitmire, J. K., Eam, B., Benning, N., Whitton, J. L. Direct interferon-gamma signalling and cd8(+) t cell memory Journal of Immunology 2007 179:1190-1197 PMID:17617612
- Botten, J., Whitton, J. L., Barrowman, P., Sidney, J., Whitmire, J. K., Alexander, J., Ting, J. P. C., Bui, H. H., Sette, A., Buchmeier, M. J. Hla-a2-restricted protection against lethal lymphocytic choriomeningitis Journal of Virology 2007 81:2307-2317 DOI:10.1128/jvi.02063-06 PMID:17166907
- Crocker, S. J., Whitmire, J. K., Frausto, R. F., Chertboonmuang, P., Soloway, P. D., Whitton, J. L., Campbell, I. L. Persistent macrophage/microglial activation and myelin disruption after experimental autoimmune encephalomyelitis in tissue inhibitor of metalloproteinase-1-deficient mice American Journal of Pathology 2006 169:2104-2116 DOI:10.2353/ajpath.2006.060626 PMID:17148673 PMCID:PMC1762490
- Whitmire, J. K., Benning, N., Whitton, J. L. Precursor frequency, nonlinear proliferation, and functional maturation of virus-specific CD4(+) T cells Journal of Immunology 2006 176:3028-3036 PMID:16493061
- Whitmire, J. K., Benning, N., Whitton, J. L. Cutting edge: Early ifn-gamma signaling directly enhances primary antivliwal cd4(+) t cell responses Journal of Immunology 2005 175:5624-5628 PMID:16237051
- Whitmire, J. K., Tan, J. T., Whitton, J. L. Interferon-gamma acts directly on cd8(+) t cells to increase their abundance during virus infection Journal of Experimental Medicine 2005 201:1053-1059 DOI:10.1084/jem.20041463 PMID:15809350 PMCID:PMC2213135
- Whitton, J. L., Slifka, M. K., Nussbaum, A. K., Whitmire, J. K., Liu, F. The regulation and maturation of antiviral immune responses Advances in Virus Research 2004 63:181-238 DOI:10.1016/s0065-3527(04)63003-x PMID:15530562