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Vosburg, David
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Vosburg, David

Graduate Student
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Positions

  • 2005 - Faculty Member, Harvey Mudd College , Claremont Colleges
  • 2002 - 2005 Jane Coffin Childs Postdoctoral Fellow, Harvard University

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  • Doctoral Dissertation
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Publications

recent publications
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  • Publications without PubMed PMIDs

  • academic article

    • Renteria-Gomez, M. A., Islas-Jacome, A., Pharande, S. G., Vosburg, D. A., Gamez-Montano, R. Synthesis of tris-heterocycles via a cascade IMCR/Aza Diels-Alder plus CuAAC strategy Frontiers in Chemistry  2019 7  DOI:10.3389/fchem.2019.00546  PMID:31448260  PMCID:PMC6691067
    • Shimizu, E. A., Cory, B., Hoang, J., Castro, G. G., Jung, M. E., Vosburg, D. A. Aqueous dearomatization/Diels-Alder cascade to a grandifloracin precursor Journal of Chemical Education  2019 96:998-1001  DOI:10.1021/acs.jchemed.8b00857
    • Kearney, S. E., Zahoranszky-Kohalmi, G., Brimacombe, K. R., Henderson, M. J., Lynch, C., Zhao, T., Wan, K. K., Itkin, Z., Dillon, C., Shen, M., Cheff, D. M., Lee, T. D., et al. Canvass: a crowd-sourced, natural-product screening library for exploring biological space ACS Central Science  2018 4:1727-1741  DOI:10.1021/acscentsci.8b00747  PMID:30648156  PMCID:PMC6311695
    • Kron, K. J., Kosich, M., Cave, R. J., Vosburg, D. A. Divergent Diels-Alder reactions in the biosynthesis and synthesis of endiandric-type tetracycles: a computational study Journal of Organic Chemistry  2018 83:10941-10947  DOI:10.1021/acs.joc.8b01594  PMID:30113843
    • Bin Go, E., Wetzler, S. P., Kim, L. J., Chang, A. Y., Vosburg, D. A. Concise, diastereoconvergent synthesis of endiandric-type tetracycles by iterative cross coupling Tetrahedron  2016 72:3790-3794  DOI:10.1016/j.tet.2016.02.040
    • Go, E. B., Srisuknimit, V., Cheng, S. L., Vosburg, D. A. Self-assembly, guest capture, and NMR spectroscopy of a metal-organic cage in water Journal of Chemical Education  2016 93:368-371  DOI:10.1021/acs.jchemed.5b00714
    • Nacsa, E. D., Fielder, B. C., Wetzler, S. P., Srisuknimit, V., Litz, J. P., Van Vleet, M. J., Quach, K., Vosburg, D. A. Direct, biomimetic synthesis of (+)-artemone via a stereoselective, organocatalytic cyclization Synthesis-Stuttgart  2015 47:2599-2602  DOI:10.1055/s-0034-1380684
    • Aldrich, T. J., Rolshausen, P. E., Roper, M. C., Reader, J. M., Steinhaus, M. J., Rapicavoli, J., Vosburg, D. A., Maloney, K. N. Radicinin from Cochliobolus sp inhibits Xylella fastidiosa, the causal agent of Pierce's Disease of grapevine Phytochemistry  2015 116:130-137  DOI:10.1016/j.phytochem.2015.03.015  PMID:25892412
    • Gan, Q., Ronson, T. K., Vosburg, D. A., Thoburn, J. D., Nitschke, J. R. Cooperative loading and release behavior of a metal-organic receptor Journal of the American Chemical Society  2015 137:1770-1773  DOI:10.1021/ja5120437  PMID:25615799
    • Patterson, A. L., May, M. D., Visser, B. J., Kislukhin, A. A., Vosburg, D. A. Solvent-free synthesis and fluorescence of a thiol-reactive sensor for undergraduate organic laboratories Journal of Chemical Education  2013 90:1685-1687  DOI:10.1021/ed400445j  PMID:24415795  PMCID:PMC3885416
    • Lipshutz, B. H., Boskovic, Z., Crowe, C. S., Davis, V. K., Whittemore, H. C., Vosburg, D. A., Wenzel, A. G. "Click" and olefin metathesis chemistry in water at room temperature enabled by biodegradable micelles Journal of Chemical Education  2013 90:1514-1517  DOI:10.1021/ed300893u
    • Wan, K. K., Evans-Klock, C. D., Fielder, B. C., Vosburg, D. A. Synthesis of cis- and trans-davanoids: artemone, hydroxydavanone, isodavanone, and nordavanone Synthesis-Stuttgart  2013 45:1541-1545  DOI:10.1055/s-0033-1338429
    • Cunningham, A. D., Ham, E. Y., Vosburg, D. A. Chemoselective reactions of citral: green syntheses of natural perfumes for the undergraduate organic laboratory Journal of Chemical Education  2011 88:322-324  DOI:10.1021/ed100539m
    • Wan, K. K., Litz, J. P., Vosburg, D. A. Two-step, stereoselective synthesis of linalyl oxides by asymmetric allylic O-alkylation Tetrahedron-Asymmetry  2010 21:2425-2428  DOI:10.1016/j.tetasy.2010.08.011
    • Nishimura, R. T., Giammanco, C. H., Vosburg, D. A. Green, enzymatic syntheses of divanillin and diapocynin for the organic, biochemistry, or advanced general chemistry laboratory Journal of Chemical Education  2010 87:526-527  DOI:10.1021/ed8001607
    • Wong, T. C., Sultana, C. M., Vosburg, D. A. A green, enantioselective synthesis of warfarin for the undergraduate organic laboratory Journal of Chemical Education  2010 87:194-195  DOI:10.1021/ed800040m
    • Morrison, K. C., Litz, J. P., Scherpelz, K. P., Dossa, P. D., Vosburg, D. A. A concise, biomimetic total synthesis of (+)-davanone Organic Letters  2009 11:2217-2218  DOI:10.1021/ol900697w  PMID:19366191
    • Vosburg, D. A. Teaching organic synthesis: a comparative case study approach Journal of Chemical Education  2008 85:1519-1523  DOI:10.1021/ed085p1519
    • Frueh, D. P., Arthanari, H., Koglin, A., Vosburg, D. A., Bennett, A. E., Walsh, C. T., Wagner, G. Dynamic thiolation-thioesterase structure of a non-ribosomal peptide synthetase Nature  2008 454:903-906  DOI:10.1038/nature07162  PMID:18704088  PMCID:PMC2597408
    • Kelly, W. L., Boyne, M. T., Yeh, E., Vosburg, D. A., Galonic, D. P., Kelleher, N. L., Walsh, C. T. Characterization of the aminocarboxycyclopropane-forming enzyme CmaC Biochemistry  2007 46:359-368  DOI:10.1021/bi061930j  PMID:17209546
    • Ueki, M., Galonic, D. P., Vaillancourt, F. H., Garneau-Tsodikova, S., Yeh, E., Vosburg, D. A., Schroeder, F. C., Osada, H., Walsh, C. T. Enzymatic generation of the antimetabolite γ,γ-dichloroaminobutyrate by NRPS and mononuclear iron halogenase action in a streptomycete Chemistry & Biology  2006 13:1183-1191  DOI:10.1016/j.chembiol.2006.09.012  PMID:17114000
    • Vaillancourt, F. H., Yeh, E., Vosburg, D. A., Garneau-Tsodikova, S., Walsh, C. T. Nature's inventory of halogenation catalysts: Oxidative strategies predominate Chemical Reviews  2006 106:3364-3378  DOI:10.1021/cr050313i  PMID:16895332
    • Frueh, D. P., Sun, Z. Y. J., Vosburg, D. A., Walsh, C. T., Hoch, J. C., Wagner, G. Non-uniformly sampled double-TROSY hNcaNH experiments for NMR sequential assignments of large proteins Journal of the American Chemical Society  2006 128:5757-5763  DOI:10.1021/ja0584222  PMID:16637644  PMCID:PMC2527460
    • Vaillancourt, F. H., Vosburg, D. A., Walsh, C. T. Dichlorination and bromination of a threonyl-S-carrier protein by the non-heme Fe-II halogenase SyrB2 ChemBioChem  2006 7:748-752  DOI:10.1002/cbic.200500480  PMID:16528784
    • Frueh, D. P., Vosburg, D. A., Walsh, C. T., Wagner, G. Determination of all nOes in H-1-C-13-Me-ILV-U-H-2-N-15 proteins with two time-shared experiments Journal of Biomolecular NMR  2006 34:31-40  DOI:10.1007/s10858-005-5338-4  PMID:16505962
    • Vaillancourt, F. H., Yeh, E., Vosburg, D. A., O'Connor, S. E., Walsh, C. T. Cryptic chlorination by a non-haem iron enzyme during cyclopropyl amino acid biosynthesis Nature  2005 436:1191-1194  DOI:10.1038/nature03797  PMID:16121186
    • Vosburg, D. A., Walsh, C. T. Natural product biosynthetic assembly lines: prospects and challenges for reprogramming Ernst Schering Research Foundation Workshop  2005 261-284  PMID:15645725
    • Walsh, C. T., Kruger, R. G., Vosburg, D. A. Nature’s assembly line logic for natural products Chemtracts. Organic Chemistry  2005 18:307-320
    • degree-related publication Vanderwal, C. D., Vosburg, D. A., Weiler, S., Sorensen, E. J. An enantioselective synthesis of FR182877 provides a chemical rationalization of its structure and affords multigram quantities of its direct precursor Journal of the American Chemical Society  2003 125:5393-5407  DOI:10.1021/ja021472b  PMID:12720453
    • degree-related publication Vosburg, D. A., Weiler, S., Sorensen, E. Concise stereocontrolled routes to fumagillol, fumagillin, and TNP-470 Chirality  2003 15:156-166  DOI:10.1002/chir.10181  PMID:12520508
    • degree-related publication Vosburg, D. A., Vanderwal, C. D., Sorensen, E. J. A synthesis of (+)-FR182877, featuring tandem transannular Diels-Alder reactions inspired by a postulated biogenesis Journal of the American Chemical Society  2002 124:4552-4553  DOI:10.1021/ja025885o  PMID:11971689
    • degree-related publication Vanderwal, C. D., Vosburg, D. A., Sorensen, E. J. Intramolecular allenolate acylations in studies toward a synthesis of FR182877 Organic Letters  2001 3:4307-4310  DOI:10.1021/ol016994v  PMID:11784204
    • Snyder, S. A., Vosburg, D. A., Jarvis, M. G., Markgraf, J. H. Intramolecular hetero Diels-Alder routes to γ-carboline alkaloids Tetrahedron  2000 56:5329-5335  DOI:10.1016/s0040-4020(00)00468-3
    • degree-related publication Vanderwal, C. D., Vosburg, D. A., Weiler, S., Sorensen, E. J. Postulated biogenesis of WS9885B and progress toward an enantioselective synthesis Organic Letters  1999 1:645-648  DOI:10.1021/ol990723r  PMID:10823194
    • degree-related publication Vosburg, D. A., Weiler, S., Sorensen, E. J. A concise synthesis of fumagillol Angewandte Chemie - International Edition  1999 38:971-974  DOI:10.1002/(SICI)1521-3773(19990401)38:7<971::AID-ANIE971>3.0.CO;2-W
    • Markgraf, J. H., Snyder, S. A., Vosburg, D. A. A concise route to isocanthin-6-one Tetrahedron Letters  1998 39:1111-1112  DOI:10.1016/s0040-4039(97)10794-8
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Background

education and training

  • Ph.D. in Chemistry, Scripps Research 1997 - 2002
  • B.A. in Chemistry, Williams College 1993 - 1997

advisee of

  • graduate advising relationship

    • Sorensen, Erik J., Ph.D.  candidacy, 1998 - 2002
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Contact

full name

  • David Andrew Vosburg

geographic location

  • Scripps California 
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Identity

ORCID iD

  • ORCID iD http://orcid.org/0000-0003-3424-5471

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