recent publications
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academic article
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Lai, J. I., Leman, L. J., Ku, S., Vickers, C. J., Olsen, C. A., Montero, A., Ghadiri, M. R., Gottesfeld, J. M.
Cyclic tetrapeptide HDAC inhibitors as potential therapeutics for spinal muscular atrophy: Screening with iPSC-derived neuronal cells
Bioorganic & Medicinal Chemistry Letters
2017
27:3289-3293
DOI:10.1016/j.bmcl.2017.06.027
PMID:28648462
- Lee, J., Moraes-Vieira, P. M., Castoldi, A., Aryal, P., Yee, E. U., Vickers, C., Parnas, O., Donaldson, C. J., Saghatelian, A., Kahn, B. B. Branched fatty acid esters of hdroxy fatty acids (FAHFAs) protect against colitis by regulating gut innate and adaptive immune responses Journal of Biological Chemistry 2016 291:22207-22217 DOI:10.1074/jbc.M115.703835 PMID:27573241 PMCID:PMC5064000
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Vickers, C. J., Gonzalez-Paez, G. E., Wolan, D. W.
Discovery of a highly selective caspase-3 substrate for imaging live cells
ACS Chemical Biology
2014
9:2199-2203
DOI:10.1021/cb500586p
PMID:25133295
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Vickers, C. J., Gonzalez-Paez, G. E., Litwin, K. M., Umotoy, J. C., Coutsias, E. A., Wolan, D. W.
Selective inhibition of initiator versus executioner caspases using small peptides containing unnatural amino acids
ACS Chemical Biology
2014
9:2194-2198
DOI:10.1021/cb5004256
PMID:25079698
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Vickers, C. J., Gonzalez-Paez, G. E., Wolan, D. W.
Selective detection and inhibition of active caspase-3 in cells with optimized peptides
Journal of the American Chemical Society
2013
135:12869-12876
DOI:10.1021/ja406399r
PMID:23915420
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Vickers, C. J., Gonzalez-Paez, G. E., Umotoy, J. C., Cayanan-Garrett, C., Brown, S. J., Wolan, D. W.
Small-molecule procaspase activators identified using fluorescence polarization
ChemBioChem
2013
14:1419-1422
DOI:10.1002/cbic.201300315
PMID:23836614
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Vickers, C. J., Gonzalez-Paez, G. E., Wolan, D. W.
Selective Detection of Caspase-3 versus Caspase-7 Using Activity-Based Probes with Key Unnatural Amino Acids
ACS Chemical Biology
2013
8:1558-1566
DOI:10.1021/cb400209w
PMID:23614665
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Vickers, C. J., Olsen, C. A., Leman, L. J., Ghadiri, M. R.
Discovery of HDAC inhibitors that lack an active site Zn(2+)-binding functional group
ACS Medicinal Chemistry Letters
2012
3:505-508
DOI:10.1021/ml300081u
PMID:24900500
PMCID:PMC4025844
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Hutt, D. M., Olsen, C. A., Vickers, C. J., Herman, D., Chalfant, M. A., Montero, A., Leman, L. J., Burkle, R., Maryanoff, B. E., Balch, W. E., Ghadiri, M. R.
Potential agents for treating cystic fibrosis: cyclic tetrapeptides that restore trafficking and activity of delta F508-CFTR
ACS Medicinal Chemistry Letters
2011
2:703-707
DOI:10.1021/ml200136e
PMID:21984958
PMCID:PMC3187562
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Vickers, C. J., Mei, T. S., Yu, J. Q.
Pd(II)-catalyzed o-C-H acetoxylation of phenylalanine and ephedrine derivatives with MeCOOO(t)Bu/Ac2O
Organic Letters
2010
12:2511-2513
DOI:10.1021/ol1007108
PMID:20446711
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