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Tubbs, Julie
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Tubbs, Julie

Graduate Student
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Positions

  • 2015 - Senior Scientist, Molecular Assemblies

Websites

  • Doctoral Dissertation
  • Publications
  • Background
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Publications

recent publications
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  • Publications without PubMed PMIDs

  • academic article

    • Wilkinson, O. J., Latypov, V., Tubbs, J. L., Millington, C. L., Morita, R., Blackburn, H., Marriott, A., McGown, G., Thorncroft, M., Watson, A. J., Connolly, B. A., Grasby, J. A., et al. Alkyltransferase-like protein (atl1) distinguishes alkylated guanines for DNA repair using cation-pi interactions Proceedings of the National Academy of Sciences of the United States of America  2012 109:18755-18760  DOI:10.1073/pnas.1209451109  PMID:23112169  PMCID:PMC3503161
    • Latypov, V. F., Tubbs, J. L., Watson, A. J., Marriott, A. S., McGown, G., Thorncroft, M., Wilkinson, O. J., Senthong, P., Butt, A., Arvai, A. S., Millington, C. L., Povey, A. C., et al. Atl1 regulates choice between global genome and transcription-coupled repair of o-6-alkylguanines Molecular Cell  2012 47:50-60  DOI:10.1016/j.molcel.2012.04.028  PMID:22658721  PMCID:PMC3398191
    • Tubbs, J. L., Tainer, J. A. P53 conformational switching for selectivity may reveal a general solution for specific DNA binding EMBO Journal  2011 30:2099-2100  DOI:10.1038/emboj.2011.133  PMID:21629273  PMCID:PMC3117650
    • Tubbs, J. L., Tainer, J. A. Alkyltransferase-like proteins: Molecular switches between DNA repair pathways Cellular and Molecular Life Sciences  2010 67:3749-3762  DOI:10.1007/s00018-010-0405-8  PMID:20502938  PMCID:PMC3088651
    • Aramini, J. M., Tubbs, J. L., Kanugula, S., Rossi, P., Ertekin, A., Maglaqui, M., Hamilton, K., Ciccosanti, C. T., Jiang, M., Xiao, R., Soong, T. T., Rost, B., et al. Structural basis of o(6)-alkylguanine recognition by a bacterial alkyltransferase-like DNA repair protein Journal of Biological Chemistry  2010 285:13736-13741  DOI:10.1074/jbc.M109.093591  PMID:20212037  PMCID:PMC2859536
    • Fang, Q. M., Kanugula, S., Tubbs, J. L., Tainer, J. A., Pegg, A. E. Repair of o(4)-alkylthymine by o(6)-alkylguanine-DNA alkyltransferases Journal of Biological Chemistry  2010 285:8185-8195  DOI:10.1074/jbc.M109.045518  PMID:20026607  PMCID:PMC2832970
    • Tubbs, J. L., Latypov, V., Kanugula, S., Butt, A., Melikishvili, M., Kraehenbuehl, R., Fleck, O., Marriott, A., Watson, A. J., Verbeek, B., McGown, G., Thorncroft, M., et al. Flipping of alkylated DNA damage bridges base and nucleotide excision repair Nature  2009 459:808-813  DOI:10.1038/nature08076  PMID:19516334  PMCID:PMC2729916
    • Fang, Q. M., Noronha, A. M., Murphy, S. P., Wilds, C. J., Tubbs, J. L., Tainer, J. A., Chowdhury, G., Guengerich, F. P., Pegg, A. E. Repair of o(6)-g-alkyl-o(6)-g interstrand cross-links by human o(6)-alkylguanine-DNA alkyltransferase Biochemistry  2008 47:10892-10903  DOI:10.1021/bi8008664  PMID:18803403  PMCID:PMC2632579
    • Tubbs, J. L., Pegg, A. E., Tainer, J. A. DNA binding, nucleotide flipping, and the helix-turn-helix motif in base repair by o-6-alkylguanine-DNA alkyltransferase and its implications for cancer chemotherapy DNA Repair  2007 6:1100-1115  DOI:10.1016/j.dnarep.2007.03.011  PMID:17485252  PMCID:PMC1993358
    • degree-related publication Tubbs, J. L., Tainer, J. A., Getzoff, E. D. Crystallographic structures of Discosoma red fluorescent protein with immature and mature chromophores: Linking peptide bond trans-cis isomerization and acylimine formation in chromophore maturation Biochemistry  2005 44:9833-9840  DOI:10.1021/bi0472907  PMID:16026155
  • chapter

    • Tubbs, J. L. DNA damage: alkylation Encyclopedia of biological chemistry. 9-15. 2013
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Background

education and training

  • Ph.D. in Biology, Scripps Research 1998 - 2004
  • B.S., Loyola Marymount University 1998

credentials

  • MicroMBA, 2014

advisee of

  • graduate advising relationship

    • Getzoff, Elizabeth, Ph.D.  candidacy, 1999 - 2004
  • postdoc or fellow advising relationship

    • Getzoff, Elizabeth, Ph.D.  candidacy, 2005 - 2013
    • Tainer, John, Ph.D.  candidacy, 2005 - 2013
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Contact

full name

  • Julie Lunyee Tubbs

geographic location

  • Scripps California 

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