recent publications
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academic article
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Zheng, J., Strutzenberg, T. S., Reich, A., Dharmarajan, V., Pascal, B. D., Crynen, G. C., Novick, S. J., Garcia-Ordonez, R. D., Griffin, P. R.
Comparative Analysis of Cleavage Specificities of Immobilized Porcine Pepsin and Nepenthesin II under Hydrogen/Deuterium Exchange Conditions
Analytical Chemistry
2020
92:11018-11028
DOI:10.1021/acs.analchem.9b05694
PMID:32658454
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Berman, H. M., Adams, P. D., Bonvin, A. A., Burley, S. K., Carragher, B., Chiu, W., DiMaio, F., Ferrin, T. E., Gabanyi, M. J., Goddard, T. D., Griffin, P. R., Haas, J., et al.
Federating structural models and data: outcomes from a workshop on archiving integrative structures
Structure
2019
27:1745-1759
DOI:10.1016/j.str.2019.11.002
PMID:31780431
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Zheng, J., Strutzenberg, T., Pascal, B. D., Griffin, P. R.
Protein dynamics and conformational changes explored by hydrogen/deuterium exchange mass spectrometry
Current Opinion in Structural Biology
2019
58:305-313
DOI:10.1016/j.sbi.2019.06.007
PMID:31351767
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Masson, G. R., Burke, J. E., Ahn, N. G., Anand, G. S., Borchers, C., Brier, S., Bou-Assaf, G. M., Engen, J. R., Englander, S. W., Faber, J., Garlish, R., Griffin, P. R., et al.
Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments
Nature Methods
2019
16:595-602
DOI:10.1038/s41592-019-0459-y
PMID:31249422
PMCID:PMC6614034
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Strutzenberg, T. S., Garcia-Ordonez, R. D., Novick, S. J., Park, H., Chang, M. R., Doebellin, C., He, Y., Patouret, R., Kamenecka, T. M., Griffin, P. R.
HDX-MS reveals structural determinants for RORγ hyperactivation by synthetic agonists
Elife
2019
8
DOI:10.7554/eLife.47172
PMID:31172947
PMCID:PMC6579513
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Chang, M. R., Ciesla, A., Strutzenberg, T. S., Novick, S. J., He, Y., Garcia-Ordonez, R. D., Frkic, R. L., Bruning, J. B., Kamenecka, T. M., Griffin, P. R.
Unique polypharmacology nuclear receptor modulator blocks inflammatory signaling pathways
ACS Chemical Biology
2019
14:1051-1062
DOI:10.1021/acschembio.9b00236
PMID:30951276
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Kim, H., Wrann, C. D., Jedrychowski, M., Vidoni, S., Kitase, Y., Nagano, K., Zhou, C., Chou, J., Parkman, V. J. A., Novick, S. J., Strutzenberg, T. S., Pascal, B. D., et al.
Irisin mediates effects on bone and fat via αV integrin receptors
Cell
2018
175:1756-1768
DOI:10.1016/j.cell.2018.10.025
PMID:30550785
PMCID:PMC6298040
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Zhang, C., Konermann, S., Brideau, N. J., Lotfy, P., Wu, X., Novick, S. J., Strutzenberg, T., Griffin, P. R., Hsu, P. D., Lyumkis, D.
Structural basis for the RNA-guided ribonuclease activity of CRISPR-Cas13d
Cell
2018
175:212-223
DOI:10.1016/j.cell.2018.09.001
PMID:30241607
- Islam, Z., Gurevic, I., Strutzenberg, T. S., Ghosh, A. K., Iqbal, T., Kohen, A. Bacterial versus human thymidylate synthase: Kinetics and functionality PLoS One 2018 13 DOI:10.1371/journal.pone.0196506 PMID:29715278 PMCID:PMC5929524
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Lin, H., Long, J. Z., Roche, A. M., Svensson, K. J., Dou, F. Y., Chang, M. R., Strutzenberg, T., Ruiz, C., Cameron, M. D., Novick, S. J., Berdan, C. A., Louie, S. M., et al.
Discovery of hydrolysis-resistant isoindoline N-Acyl amino acid analogues that stimulate mitochondrial respiration
Journal of Medicinal Chemistry
2018
61:3224-3230
DOI:10.1021/acs.jmedchem.8b00029
PMID:29533650
- Islam, Z., Strutzenberg, T. S., Ghosh, A. K., Kohen, A. Activation of two sequential H transfers in the thymidylate synthase catalyzed reaction ACS Catalysis 2015 5:6061-6068 DOI:10.1021/acscatal.5b01332 PMID:26576323 PMCID:PMC4643671
- Islam, Z., Strutzenberg, T. S., Gurevic, I., Kohen, A. Concerted versus stepwise mechanism in thymidylate synthase Journal of the American Chemical Society 2014 136:9850-9853 DOI:10.1021/ja504341g PMID:24949852 PMCID:PMC4105062
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