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Strutzenberg, Timothy
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Strutzenberg, Timothy

Graduate Student
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Publications

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  • academic article

    • degree-related publication Zheng, J., Strutzenberg, T. S., Reich, A., Dharmarajan, V., Pascal, B. D., Crynen, G. C., Novick, S. J., Garcia-Ordonez, R. D., Griffin, P. R. Comparative Analysis of Cleavage Specificities of Immobilized Porcine Pepsin and Nepenthesin II under Hydrogen/Deuterium Exchange Conditions Analytical Chemistry  2020 92:11018-11028  DOI:10.1021/acs.analchem.9b05694  PMID:32658454
    • degree-related publication Berman, H. M., Adams, P. D., Bonvin, A. A., Burley, S. K., Carragher, B., Chiu, W., DiMaio, F., Ferrin, T. E., Gabanyi, M. J., Goddard, T. D., Griffin, P. R., Haas, J., et al. Federating structural models and data: outcomes from a workshop on archiving integrative structures Structure  2019 27:1745-1759  DOI:10.1016/j.str.2019.11.002  PMID:31780431
    • degree-related publication Zheng, J., Strutzenberg, T., Pascal, B. D., Griffin, P. R. Protein dynamics and conformational changes explored by hydrogen/deuterium exchange mass spectrometry Current Opinion in Structural Biology  2019 58:305-313  DOI:10.1016/j.sbi.2019.06.007  PMID:31351767
    • degree-related publication Masson, G. R., Burke, J. E., Ahn, N. G., Anand, G. S., Borchers, C., Brier, S., Bou-Assaf, G. M., Engen, J. R., Englander, S. W., Faber, J., Garlish, R., Griffin, P. R., et al. Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments Nature Methods  2019 16:595-602  DOI:10.1038/s41592-019-0459-y  PMID:31249422  PMCID:PMC6614034
    • degree-related publication Strutzenberg, T. S., Garcia-Ordonez, R. D., Novick, S. J., Park, H., Chang, M. R., Doebellin, C., He, Y., Patouret, R., Kamenecka, T. M., Griffin, P. R. HDX-MS reveals structural determinants for RORγ hyperactivation by synthetic agonists Elife  2019 8  DOI:10.7554/eLife.47172  PMID:31172947  PMCID:PMC6579513
    • degree-related publication Chang, M. R., Ciesla, A., Strutzenberg, T. S., Novick, S. J., He, Y., Garcia-Ordonez, R. D., Frkic, R. L., Bruning, J. B., Kamenecka, T. M., Griffin, P. R. Unique polypharmacology nuclear receptor modulator blocks inflammatory signaling pathways ACS Chemical Biology  2019 14:1051-1062  DOI:10.1021/acschembio.9b00236  PMID:30951276
    • degree-related publication Kim, H., Wrann, C. D., Jedrychowski, M., Vidoni, S., Kitase, Y., Nagano, K., Zhou, C., Chou, J., Parkman, V. J. A., Novick, S. J., Strutzenberg, T. S., Pascal, B. D., et al. Irisin mediates effects on bone and fat via αV integrin receptors Cell  2018 175:1756-1768  DOI:10.1016/j.cell.2018.10.025  PMID:30550785  PMCID:PMC6298040
    • degree-related publication Zhang, C., Konermann, S., Brideau, N. J., Lotfy, P., Wu, X., Novick, S. J., Strutzenberg, T., Griffin, P. R., Hsu, P. D., Lyumkis, D. Structural basis for the RNA-guided ribonuclease activity of CRISPR-Cas13d Cell  2018 175:212-223  DOI:10.1016/j.cell.2018.09.001  PMID:30241607
    • Islam, Z., Gurevic, I., Strutzenberg, T. S., Ghosh, A. K., Iqbal, T., Kohen, A. Bacterial versus human thymidylate synthase: Kinetics and functionality PLoS One  2018 13  DOI:10.1371/journal.pone.0196506  PMID:29715278  PMCID:PMC5929524
    • degree-related publication Lin, H., Long, J. Z., Roche, A. M., Svensson, K. J., Dou, F. Y., Chang, M. R., Strutzenberg, T., Ruiz, C., Cameron, M. D., Novick, S. J., Berdan, C. A., Louie, S. M., et al. Discovery of hydrolysis-resistant isoindoline N-Acyl amino acid analogues that stimulate mitochondrial respiration Journal of Medicinal Chemistry  2018 61:3224-3230  DOI:10.1021/acs.jmedchem.8b00029  PMID:29533650
    • Islam, Z., Strutzenberg, T. S., Ghosh, A. K., Kohen, A. Activation of two sequential H transfers in the thymidylate synthase catalyzed reaction ACS Catalysis  2015 5:6061-6068  DOI:10.1021/acscatal.5b01332  PMID:26576323  PMCID:PMC4643671
    • Islam, Z., Strutzenberg, T. S., Gurevic, I., Kohen, A. Concerted versus stepwise mechanism in thymidylate synthase Journal of the American Chemical Society  2014 136:9850-9853  DOI:10.1021/ja504341g  PMID:24949852  PMCID:PMC4105062
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Background

education and training

  • Ph.D. in Chemical Biology, Scripps Research 2015 -
  • B.A. in Chemistry, University of Iowa 2011 - 2015
  • B.S. in Biochemistry, University of Iowa 2011 - 2015

advisee of

  • graduate advising relationship

    • Griffin, Patrick, Ph.D.  candidacy, 2016 -
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Contact

full name

  • Timothy Silas Strutzenberg

geographic location

  • Scripps Florida 

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